Xu, Jing published the artcileIn silico screening of potential anti-COVID-19 bioactive natural constituents from food sources by molecular docking, Recommanded Product: 2-((5-Nitrothiazol-2-yl)carbamoyl)phenyl acetate, the main research area is human covid19 virus anticoronaviral agent mol docking; Angiotensin-converting enzyme 2; COVID-19; Chinese hawthorn and blackberry; Molecular docking; Red wine; SARS-CoV-2 3CL hydrolytic enzyme.
The aim of this study was to seek potential natural compounds that can resist COVID-19 using computer virtual screening technol. through mol. docking of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) 3CL hydrolytic enzyme (3CLpro) and angiotensin-converting enzyme 2 (ACE2). Mol. docking was achieved by using the Autodock Vina software. The natural phytocompounds acting on 3CLpro and ACE2 were then selected from the Traditional Chinese Medicine Systems Pharmacol. Database and Anal. Platform. This was followed by speculation on the mechanism of action of phytocompounds. Six potential natural anti-COVID-19 phytocompounds were selected and were evaluated for absorption, distribution, metabolism and excretion (ADME) and Lipinski rules. The content of the six phytocompounds in various fruits and vegetables was determined via a literature search. Red wine, Chinese hawthorn, and blackberry were recommended as supplements because they contained antiviral phytocompounds. Red wine, Chinese hawthorn, and blackberry show promise for resisting COVID-19 and are thus recommended as supplements to prevent the infection of COVID-19 during its outbreak period.
Nutrition (New York, NY, United States) published new progress about Adsorption. 55981-09-4 belongs to class esters-buliding-blocks, name is 2-((5-Nitrothiazol-2-yl)carbamoyl)phenyl acetate, and the molecular formula is C12H9N3O5S, Recommanded Product: 2-((5-Nitrothiazol-2-yl)carbamoyl)phenyl acetate.
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