Siddalinga Swamy, M. S. published the artcileRP-HPLC method for simultaneous estimation of nitazoxanide and ofloxacin in bulk drug and in pharmaceutical formulation, Recommanded Product: 2-((5-Nitrothiazol-2-yl)carbamoyl)phenyl acetate, the main research area is nitazoxanide ofloxacin pharmaceutical formulation reverse phase high; performance liquid chromatog.
A simple, precise, accurate, rapid and reproducible reverse phase high performance liquid chromatog. procedure was developed for simultaneous determination of nitazoxanide and ofloxacin in tablet dosage form was carried on an Inert ODS-3V (250X4.6 nm, 5micro) column using a mobile phase consisting of methanol and buffer (20:80 volume/volume) with a pH3.3 ± at a rate of 1.5 mL/min and the detection was carried out at 230 nm. The linearity was found to be in the range of 5-60μg/mL and 2-24μg/mL Nitazoxanide and Ofloxacin resp. with (r2=0.9990, and r2=0.9994). The peaks obtained were sharp having clear baseline separation with a retention time of 9.093μ 0.03 and 5.946μ 0.03 min for Nitazoxanide and Ofloxacin resp. The results of the anal. were validated statistically and recovery studies confirmed the accuracy of the proposed method.
International Journal of PharmTech Research published new progress about Flow. 55981-09-4 belongs to class esters-buliding-blocks, name is 2-((5-Nitrothiazol-2-yl)carbamoyl)phenyl acetate, and the molecular formula is C12H9N3O5S, Recommanded Product: 2-((5-Nitrothiazol-2-yl)carbamoyl)phenyl acetate.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics