Laghari, Saif-ul-Rehman published the artcileAssessment of drug utilization of antimicrobials in different infectious diseases at various clinics of Sanghar, Pakistan, Category: esters-buliding-blocks, the main research area is antimicrobials infectious diseases metronidazole.
The aim was to assess the frequency of antimicrobial medications in various diseases at clin. setups. This study was conducted for a period of six months from Apr. 2019 to Sept. 2019. A total of 10 Clin. setups were part of this study including the OPDs of general practitioners. A total of 1000 prescription were collected by purposive sampling. A specially designed data form was used for collecting the data The data were analyzed and compared with WHO guidelines. A drug utilization study of antimicrobial agents was carried out from 1000 prescriptions. A total of 1060 antimicrobial medications were prescribed. Mostly observed patients with microbial infection came from 51-60 years of age group. Most common observed microbial diseases are upper respiratory tract infections (22.4%), acute gastroenteritis (20.2%) and urinary tract infections (16.4%). The percentage of drugs prescribed with the generic name was only 10%. This study showed that only 31.5% patients tested from laboratory for disease diagnosis. Among the wide range of antimicrobials, antibiotics were the most common prescribed drug i.e. 68% of total antimicrobial drugs. Most commonly prescribed antibiotic drugs were Co-amoxiclave (26.8%) followed by levofloxacin (18.5%), and ciprofloxacin (17.6%). Most commonly used antiprotozoal drug was metronidazole i.e. 60% of total prescribed antiprotozoal drugs, while commonly prescribed anti-fungal drug was fluconazole i.e. 44.2% of total prescribed antifungal drugs and most commonly antiviral drug was Acyclovir i.e. 46%. As compared with WHO guidelines, the utilization of Injectable was on higher side i.e. 28%. The conclusion revealed that drug utilization practice was not appropriate in accordance to WHO prescribing indicators. Polypharmacy and over prescriptions of antimicrobials was too high which leads to poor treatment outcomes and high economic burden on patients. Irrational drugs therapy is one of the top leading causes of death in developing countries including Pakistan and the results of our study also agree with the above fact.
Latin American Journal of Pharmacy published new progress about Acne. 55981-09-4 belongs to class esters-buliding-blocks, name is 2-((5-Nitrothiazol-2-yl)carbamoyl)phenyl acetate, and the molecular formula is C12H9N3O5S, Category: esters-buliding-blocks.
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