Hwang, D. I. published the artcileWound healing related biological activities and chemical composition of absolute from Hemistepta lyrata bunge flower, HPLC of Formula: 929-77-1, the main research area is Hemistepta flower wound healing absolute chem composition.
The Hemistepta lyrata Bunge flower has various biol. and pharmacol. effects, but effects of its absolute on skin regeneration or wound healing-linked responses remain unknown. In the present study, effects of Hemistepta lyrata Bunge flower absolute were explored on the proliferation and migration of normal human keratinocytes as well as the composition of absolute from Hemistepta lyrata Bunge flower was analyzed using gas chromatog.-mass spectrometry. Hemistepta lyrata Bunge flower absolute stimulated both proliferation and migration of the keratinocytes. It also enhanced the phosphorylation of extracellular signal-regulated kinase 1/2 and serine/threonine-specific protein kinase in human keratinocytes. Moreover, the Hemistepta lyrata Bunge flower absolute increased the sprout outgrowth of human keratinocytes. Gas chromatog.-mass spectrometry anal. of Hemistepta lyrata Bunge flower absolute allowed identification of 16 compounds These findings indicated that the absolute promoted the migration and proliferation of keratinocytes. Therefore, Hemistepta lyrata Bunge flower absolute might play a beneficial role in skin regeneration or wound healing by elevating migration and proliferation of keratinocytes.
Indian Journal of Pharmaceutical Sciences published new progress about Cell migration. 929-77-1 belongs to class esters-buliding-blocks, name is Methyl docosanoate, and the molecular formula is C23H46O2, HPLC of Formula: 929-77-1.
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