Nguyen, Duc Ba published the artcileApplication of plasma jet to the inhibition of the proliferation of hepatic malignant cells via reactive oxygen species generation, Safety of 2′,7′-Dichloro-3-oxo-3H-spiro[isobenzofuran-1,9′-xanthene]-3′,6′-diyl diacetate, the main research area is hepatic malignant cell proliferation dielec barrier plasma jet discharge.
In vitro treatment of hepatic malignant cells with plasma-activated medium conjugated with gemcitabine was investigated with a He plasma jet generated by a two-ring dielec. barrier discharge (DBD) reactor. The DBD reactor was operated by high-voltage pulses of alternating polarity (frequency: 20 kHz; pulse width: 4 us). The electron d. of plasma plume was estimated to be 9×1012 to 10×1012 cm-3, and the jet temperature was around 36°C. The plasma jet exhibited the inhibitory effects on the growth of hepatic malignant cells via the generation of reactive oxygen species, which could be potentially applicative in anticancer therapies. The optimization of the operating parameters and configuration of the plasma jet would help increase the possibility in practical cancer treatments.
Plasma Processes and Polymers published new progress about Antitumor agents. 2044-85-1 belongs to class esters-buliding-blocks, name is 2′,7′-Dichloro-3-oxo-3H-spiro[isobenzofuran-1,9′-xanthene]-3′,6′-diyl diacetate, and the molecular formula is C24H14Cl2O7, Safety of 2′,7′-Dichloro-3-oxo-3H-spiro[isobenzofuran-1,9′-xanthene]-3′,6′-diyl diacetate.
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