Danta, Chhanda Charan published the artcileCNS Penetration Ability: A Critical Factor for Drugs in the Treatment of SARS-CoV-2 Brain Infection, Application of 2-((5-Nitrothiazol-2-yl)carbamoyl)phenyl acetate, the main research area is drug treatment SARS CoV 2; CNS infection; CNS penetration; COVID19; SARS-CoV-2; drug treatment; log P.
Now, it has been evidenced that Covid19 (SARS-CoV-2) infects the brain tissues. Along with this, a challenge has been raised for research professionals to find effective drugs for its treatment since the recent spread of this virus from Wuhan, China. Targeting the treatment of brain infection, it has also been a challenge that the clin. drug should have good CNS penetration ability to cross the blood-brain barrier.
ACS Chemical Neuroscience published new progress about Antiviral agents. 55981-09-4 belongs to class esters-buliding-blocks, name is 2-((5-Nitrothiazol-2-yl)carbamoyl)phenyl acetate, and the molecular formula is C12H9N3O5S, Application of 2-((5-Nitrothiazol-2-yl)carbamoyl)phenyl acetate.
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Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics