Albalat, Muriel published the artcileAn enzymatic acetal/hemiacetal conversion for the physiological temperature activation of the alkoxyamine C-ON bond homolysis, Application of Benzyl acetate, the main research area is alkoxylamine bond cleavage enzymic acetal hemiacetal conversion.
The potential of alkoxyamines as theranostic agents has been recently promoted by authors groups. The success of such an approach relies on the switch upon enzymic triggering between highly stable precursor alkoxyamines and activated alkoxyamines exhibiting fast homolysis of the C-ON bond. Hence, at 37° in water, benzyl 2-(2,2,6,6-tetramethylpiperidin-N-oxy)-3-ethoxy-3-acetoxypropanoate and benzyl 2-ditert-butylaminoxy-3-ethoxy-3-acetoxy propanoate afford tmax of 2000 s (35% conversion) and 500 s (60% conversion), resp., for the C-ON bond homolysis in the presence of Subtilisin A whereas t1/2 of ca. 42 thousand millenniums and 330 years are expected accordingly to Ea values in n-propanol. These results nicely highlight the on/off switch, provided that an enzymic activity controls the C-ON bond homolysis.
Organic Chemistry Frontiers published new progress about Activation energy. 140-11-4 belongs to class esters-buliding-blocks, name is Benzyl acetate, and the molecular formula is C9H10O2, Application of Benzyl acetate.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics