GC-MS rapid screening of eight non-steroidal anti-inflammatory drugs in health foods and traditional Chinese medicines was written by Zhu, Xiao-hong;Li, Tao;Ma, Peng-fei;Zhu, Jian-rong;Yan, Yu;Liu, Hai-jing. And the article was included in Yaowu Fenxi Zazhi in 2012.Reference of 5003-48-5 The following contents are mentioned in the article:
A GC-MS method for detection of non-steroidal anti-inflammatory drugs that illegally added in health foods and traditional Chinese medicines was established. Samples were extracted and enriched by using solvent extraction or liquid-liquid extraction method. Qual. detection was carried out by GC-MS and Scan mode. In addition, quant. anal. was performed using Selected ion monitoring (SIM) mode. The anal. capillary column was DP-5 ms (30 m×0.25 mm×0.25 μm). The oven temperature was set at 120°C (1 min) initially, it was programmed to rise to 230°C at 10°C·min-1, and then rise to 270°C at 15°C·min-1 20 min). The EI ion source was selected and the solvent was delayed by 2.5 min. The MS scanning was set at the range of 40-350 amu. Under the selected chromatog. conditions, 8 kinds of chem. drugs could get a better separation within 30 min. Then paracetamol and diclofenac sodium were detected in two batches of samples. This method was rapid, accurate, and selective, which was suitable for fast qual. detection of drugs added illegally. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5Reference of 5003-48-5).
4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Reference of 5003-48-5
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics