Highly sensitive determination of benorilate using silver nanoparticles/polyindole/reduced graphene oxide nanocomposite modified electrode was written by Li, Rong-Fang;Zhang, Sheng-Feng;Kong, Fen-Ying;Wang, Zhong-Xia;Fang, Hai-Lin;Wang, Wei. And the article was included in Journal of Electroanalytical Chemistry in 2021.SDS of cas: 5003-48-5 The following contents are mentioned in the article:
It is known that excessive intake of drugs can cause harmful side effects to the human body. Monitoring of drugs in tablets is important to control levels below allowable limits. Herein a novel electrochem. sensor for sensitive detection of benorilate was developed using silver nanoparticles-polyindole-reduced graphene oxide (AgNPs-PIn-rGO) nanocomposite. Cyclic voltammetry (CV) and differential pulse voltammetry (DPV) were used to investigate the electrochem. behavior of benorilate. The AgNPs-PIn-rGO nanocomposite exhibited outstanding electrocatalytic activity toward benorilate. In addition, the effects of scaning rate, pH and accumulation time on the performance of the electrochem. sensor were also studied. Under the optimal condition, the designed sensor showed an appreciable linear response range (0.06μM-80μM) and a low detection limit (6 nM). Meanwhile, the sensor also displayed excellent selectivity and good storage stability. More importantly, the established method was successfully applied for benorilate determination in pharmaceutical tablets and the result was satisfactory. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5SDS of cas: 5003-48-5).
4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. SDS of cas: 5003-48-5
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics