Day, Daniel M. published the artcileAn experimental investigation into the kinetics and mechanism of the aza-Michael additions of dimethyl itaconate, Recommanded Product: Dimethyl itaconate, the publication is Tetrahedron (2022), 132921, database is CAplus.
The aza-Michael addition is a versatile reaction for the modification of α,β-unsaturated carbonyl compounds with amines. The reactivity of di-Me itaconate as a bio-based Michael acceptor is explored in this work. Through its reactions with piperidine and dibutylamine, it was found that the order of reaction can be changed by the choice of catalyst, solvent, or the concentration of the amine reactant. The effectiveness of catalysts was proportional to their Lewis acidity. Competitive isomerisation of di-Me itaconate into unreactive regioisomers can be suppressed using low-polarity solvents and lower temperatures This investigation of the aza-Michael additions of di-Me itaconate has clarified the possible reaction mechanisms and optimized the protocol, supporting further use of this reaction in small mol. synthesis and modification of polymers.
Tetrahedron published new progress about 617-52-7. 617-52-7 belongs to esters-buliding-blocks, auxiliary class Alkenyl,Aliphatic hydrocarbon chain,Ester, name is Dimethyl itaconate, and the molecular formula is C7H10O4, Recommanded Product: Dimethyl itaconate.
Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics