Abadleh, Mohammed M.’s team published research in Letters in Organic Chemistry in 11 | CAS: 924-99-2

Letters in Organic Chemistry published new progress about 924-99-2. 924-99-2 belongs to esters-buliding-blocks, auxiliary class Alkenyl,Amine,Aliphatic hydrocarbon chain,Ester, name is Ethyl 3-(dimethylamino)acrylate, and the molecular formula is C7H13NO2, Safety of Ethyl 3-(dimethylamino)acrylate.

Abadleh, Mohammed M. published the artcileSynthesis and Biological Activity of Some New N1-(6-fluoro-4-oxoquinolin-8-yl)amidrazones, Safety of Ethyl 3-(dimethylamino)acrylate, the publication is Letters in Organic Chemistry (2014), 11(9), 664-670, database is CAplus.

A selected set of five N1-(6-fluoro-4-oxoquinolin-8-yl)amidrazone-3-carboxylates incorporating piperazines and related congeners has been synthesized by reacting the hydrazonoyl chloride, derived from 8-amino-6-fluoro-4-oxoquinline-3-carboxylate, with the appropriate sec-cyclic amines. Their suggested structures are supported by elemental anal., 1H NMR, 13C NMR and ESI-HRMS spectral data. These novel compounds were screened for their antitumor and antibacterial activity. While no significant antitumor activity was observed, three compounds, e.g. I, have shown moderate in vitro antibacterial activity against Gram pos. bacteria cells. Unlike the others, compound I has also shown to moderately inhibit the growth of Gram neg. bacteria.

Letters in Organic Chemistry published new progress about 924-99-2. 924-99-2 belongs to esters-buliding-blocks, auxiliary class Alkenyl,Amine,Aliphatic hydrocarbon chain,Ester, name is Ethyl 3-(dimethylamino)acrylate, and the molecular formula is C7H13NO2, Safety of Ethyl 3-(dimethylamino)acrylate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics