Transition-metal-free visible light-promoted photoredox oxidative dehydrogenative cyclization: expeditious approach to 1,2,4-thiadiazoles was written by Xiong, Zhiqiang;Zhong, Qihao;Sheng, Shouri;Chen, Junmin. And the article was included in ARKIVOC (Gainesville, FL, United States) in 2021.Reference of 2253-73-8 The following contents are mentioned in the article:
A novel visible-light-catalyzed oxidative N-S bond formation for the synthesis of 3,5-disubstituted 1,2,4-thiadiazoles I (R1 = Me, Ph, cyclopropyl, etc.; R2 = i-Pr, Ph, 3-chlorophenyl, etc.) has been developed. This protocol features a metal-free approach, green oxidant, room temperature process, broad substrate scope, good functional group tolerance, excellent yields and a one-pot reaction without the isolation of the intermediates. This study involved multiple reactions and reactants, such as Isopropylisothiocyanate (cas: 2253-73-8Reference of 2253-73-8).
Isopropylisothiocyanate (cas: 2253-73-8) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Reference of 2253-73-8
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics