AgBF4-catalyzed deoxygenative C2-amination of quinoline N-oxides with isothiocyanates was written by Xie, Long-Yong;Peng, Sha;Jiang, Li-Lin;Peng, Xia;Xia, Wen;Yu, Xianyong;Wang, Xing-Xing;Cao, Zhong;He, Wei-Min. And the article was included in Organic Chemistry Frontiers in 2019.Safety of Isopropylisothiocyanate The following contents are mentioned in the article:
A general, effective and convenient protocol for the direct synthesis of various 2-aminoquinolines I [R1 = H, 3-Me, 6-CH=CHPh, etc.; R2 = H, n-Bu, 2-pyridyl, etc.] through AgBF4-catalyzed amination of quinoline N-oxides with isothiocyanates under base-, oxidant-free and mild conditions was developed. A sequential one-pot amination/cyclization could be performed to convert the quinoline-N-oxide into benzo[4,5]imidazo[1,2-a]quinoline without isolating any reaction intermediates. This study involved multiple reactions and reactants, such as Isopropylisothiocyanate (cas: 2253-73-8Safety of Isopropylisothiocyanate).
Isopropylisothiocyanate (cas: 2253-73-8) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Safety of Isopropylisothiocyanate
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics