Mechanism of skin penetration by cercariae of S. japonicum and screening of preventive drugs was written by Wang, Yusheng;Chen, Jiayu;Song, Peizhao;Wang, Wenni;Zhou, Xiankun;Hu, Huiqin. And the article was included in Huaxi Yike Daxue Xuebao in 1989.Reference of 5003-48-5 The following contents are mentioned in the article:
The prostaglandin inhibitors aspirin and ibuprofen given orally or i.p. to mice inhibited skin penetration by Schistosoma japonicum cercariae; the penetration was not affected by the receptor antagonists diphenhydramine, chlorpheniramine, atropine, and practolol, but was inhibited by praziquantel. PGE1 in the cercaria-penetrated mouse skin was higher than that in normal skin, suggesting that prostaglandins are necessary for the penetration. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5Reference of 5003-48-5).
4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Reference of 5003-48-5
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics