Comparative effectiveness of topically applied nonsteroid antiinflammatory agents on guinea pig skin was written by Sarkany, I.;Gaylarde, P. M.;Brock, A. P.. And the article was included in Clinical and Experimental Dermatology in 1981.Safety of 4-Acetamidophenyl 2-acetoxybenzoate The following contents are mentioned in the article:
Twelve nonsteroid antiinflammatory agents and 2 antioxidants, known to have prostaglandin synthesis inhibitory activity, were tested for their ability to suppress irritant-induced epidermal thickening in the guinea pig. Salicylates and indomethacin [53-86-1] were the most active. From previous experience, this activity is thought to correspond to the behavior of these drugs in human skin. Since no antiinflammatory activity was demonstrated by the antioxidants, the unifying concept of prostaglandin synthesis inhibition as an explanation for suppression of inflammation is questioned. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5Safety of 4-Acetamidophenyl 2-acetoxybenzoate).
4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Safety of 4-Acetamidophenyl 2-acetoxybenzoate
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics