A New Facet of Azatriene Reactivity: A Short Cut to 5-Amino-3-methyl-4-(1H-pyrrol-1-yl)thiophene-2-carboxylates and 5-Amino-3-methyl-4-(1H-pyrrol-1-yl)thiophene-2-carbonitriles was written by Nedolya, Nina A.;Tarasova, Olga A.;Albanov, Alexander I.;Trofimov, Boris A.. And the article was included in European Journal of Organic Chemistry in 2018.HPLC of Formula: 2253-73-8 The following contents are mentioned in the article:
An simple and expedient approach to highly functionalized tetrasubstituted thiophenes from readily accessible starting materials [(1H-pyrrol-1-yl)allene, isothiocyanates, and alkyl 2-bromoacetates or 2-bromoacetonitrile] has been developed. The method is based on the one-pot synthesis and fast in-situ cyclization of alkyl 2-{[2-(1H-pyrrol-1-yl)buta-2,3-dienimidoyl]sulfanyl}acetates or cyanomethyl 2-(1H-pyrrol-1-yl)buta-2,3-dienimidothioates (1-aza-1,3,4-trienes) to give previously unknown thiophene-2-carboxylates and thiophene-2-carbonitriles, resp., both bearing pyrrole substituents. This study involved multiple reactions and reactants, such as Isopropylisothiocyanate (cas: 2253-73-8HPLC of Formula: 2253-73-8).
Isopropylisothiocyanate (cas: 2253-73-8) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.HPLC of Formula: 2253-73-8
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics