Synthesis of new spiro pyrrole/pyrrolizine/thiazole derivatives via (3+2) cycloaddition reactions was written by Mali, Prakash R.;Khomane, Navnath B.;Sridhar, B.;Meshram, H. M.;Likhar, Pravin R.. And the article was included in New Journal of Chemistry in 2018.Application of 2253-73-8 The following contents are mentioned in the article:
A series of spiro pyrrole/pyrrolizine/thiazole compounds, e.g., I, were synthesized using [3+2]-dipolar cycloadditions via three-component condensation reactions of ninhydrin and α-amino acids with different dipolarophiles such as maleimide, malic anhydride, 2-benzyl-2-methylcyclopent-4-ene-1,3-dione and isothiocyanates. Another four-component protocol was developed in which ninhydrin, proline, maleimide and phenacyl bromides are reacted to afford a novel library of pyrrolizine derivatives in good yields without the use of catalyst. This study involved multiple reactions and reactants, such as Isopropylisothiocyanate (cas: 2253-73-8Application of 2253-73-8).
Isopropylisothiocyanate (cas: 2253-73-8) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Application of 2253-73-8
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics