Studies on benorylate capsules formulation and their pharmacokinetics in humans was written by Chen, Jun;Tu, Xide. And the article was included in Zhongguo Yaoke Daxue Xuebao in 1997.Formula: C17H15NO5 The following contents are mentioned in the article:
Benorylate capsules were developed by triturating the material drug with the surfactant, with the purpose of improving the bioavailability compared to the tablets. The dissolution rate in vitro was determined by a paddle method and surfactant solution medium. The plasma concentration of the hydrolyzates which are salicylic acid and paracetamol from benorylate in vivo were measured by HPLC. The pharmacokinetics and bioavailability of the prepared capsules and tablets were studied. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5Formula: C17H15NO5).
4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Formula: C17H15NO5
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics