Synthesis and characterization of a new series of thiadiazole derivatives as potential anticancer agents was written by Cevik, Ulviye Acar;Osmaniye, Derya;Levent, Serkan;Saglik, Beguem Nurpelin;Cavusoglu, Betuel Kaya;Oezkay, Yusuf;Kaplancikl, Zafer Asim. And the article was included in Heterocyclic Communications in 2020.COA of Formula: C4H7NS The following contents are mentioned in the article:
The aim of this study was to determine the capacity of newly synthesized 1,3,4-thiadiazole compounds I [R = Me, allyl, Ph, etc.] as chemotherapeutic agents. The structures of the obtained compounds were elucidated using 1H-NMR, 13C-NMR and mass spectrometry. Although the thiadiazole derivatives I did not prove to be significantly cytotoxic to the tumor tissue cultures, compound I [R = phenyl] showed activity against the C6 rat brain cancer cell line (IC50 0.097 mM) at the tested concentrations This study involved multiple reactions and reactants, such as Isopropylisothiocyanate (cas: 2253-73-8COA of Formula: C4H7NS).
Isopropylisothiocyanate (cas: 2253-73-8) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.COA of Formula: C4H7NS
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics