Esterase activity in rat hepatocytes was written by Williams, Faith M.;Mutch, Elaine;Blain, Peter G.. And the article was included in Biochemical Pharmacology in 1991.Product Details of 5003-48-5 The following contents are mentioned in the article:
Hydrolysis of acetylsalicylate, benorylate, phenetsal, fluazifop Bu, and paraoxon has been studied with freshly isolated rat hepatocytes maintained as a monolayer. Acetylsalicylate and paraoxon were the poorest substrates for hydrolysis, whereas benorylate was hydrolyzed 100-fold faster. Phenetsal and fluazifop Bu were both hydrolyzed at 1/10 of the rate of benorylate. Inhibitor studies with paraoxon, BNPP, and physostigmine indicated the involvement of different carboxylesterase isoenzymes. Studies with acetylsalicylate indicated that uptake of the substrate into the hepatocyte may influence the rate of formation of the hydrolysis product. Studies of hydrolysis in hepatocytes more closely reflect in vivo hepatic hydrolysis than subcellular fractions as cytosolic and microsomal esterases can act in parallel. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5Product Details of 5003-48-5).
4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Product Details of 5003-48-5
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics