4-(N-Boc-amino)-1H-1,2,3-triazolecarbothioamides in the synthesis of a new heterocyclic [1,2,3]triazolo[4,5-e][1,4]thiazepine system was written by Syrota, Natalia A.;Kemskiy, Sergiy V.;Bol’but, Andriy V.;Chernobaev, Igor I.;Liavinets, Oleksandr S.;Vovk, Mykhailo V.. And the article was included in Chemistry of Heterocyclic Compounds in 2021.Reference of 2253-73-8 The following contents are mentioned in the article:
4-(N-Boc-amino)-1H-1,2,3-triazolecarbothioamides I [R1 = Me, Ph, 2-MeOC6H4, H2CH2CPh; R2 = Et, i-Pr, t-Bu, cyclohexyl] , obtained by a sequential treatment of 4-(N-Boc-amino)-1H-1,2,3-triazoles with n-BuLi and alkyl isothiocyanates at -78 and -60°C, reacted with Et bromoacetate, forming the resp. 4-(N-Boc-amino)-5-thioimidates II , which underwent intramol. cyclocondensation upon treatment in saturated HCl solution in dioxane, producing 8-(alkylimino)-4,8-dihydro-1H-[1,2,3]triazolo[4,5-e][1,4]thiazepin-5(6H)-ones III. This study involved multiple reactions and reactants, such as Isopropylisothiocyanate (cas: 2253-73-8Reference of 2253-73-8).
Isopropylisothiocyanate (cas: 2253-73-8) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Reference of 2253-73-8
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics