Redox-Neutral TEMPO Catalysis: Direct Radical (Hetero)Aryl C-H Di- and Trifluoromethoxylation was written by Lee, Johnny W.;Lim, Sanghyun;Maienshein, Daniel N.;Liu, Peng;Ngai, Ming-Yu. And the article was included in Angewandte Chemie, International Edition in 2020.Recommanded Product: 102-09-0 The following contents are mentioned in the article:
Applications of TEMPO· catalysis for the development of redox-neutral transformations are rare. Reported here is the first TEMPO·-catalyzed, redox-neutral C-H di- and trifluoromethoxylation of (hetero)arenes. The reaction exhibits a broad substrate scope, has high functional-group tolerance, and can be employed for the late-stage functionalization of complex druglike mols. Kinetic measurements, isolation and resubjection of catalytic intermediates, UV/visible studies, and DFT calculations support the proposed oxidative TEMPO·/TEMPO+ redox catalytic cycle. Mechanistic studies also suggest that Li2CO3 plays an important role in preventing catalyst deactivation. These findings will provide new insights into the design and development of novel reactions through redox-neutral TEMPO· catalysis. This study involved multiple reactions and reactants, such as Diphenyl carbonate (cas: 102-09-0Recommanded Product: 102-09-0).
Diphenyl carbonate (cas: 102-09-0) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Recommanded Product: 102-09-0
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics