Hirashita, Tsunehisa published the artcileA facile preparation of indium enolates and their Reformatskii- and Darzens-type reactions, Synthetic Route of 5340-78-3, the publication is Perkin 1 (2000), 825-828, database is CAplus.
Indium enolates were readily prepared by transmetalation of lithium enolates, e.g., EtO2CCH2R (R = H, Me, CHMe2, CMe3), with indium trichloride, and were subsequently reacted with aldehydes R1CHO [R1 = Ph, 2-HOC6H4, Me(CH2)6, (E)-PhCH:CH] to give β-hydroxy esters EtO2CCHRCH(OH)R1 in 48-88% yields and with moderate stereoselectivities of from 86:14 anti:syn to 67:33 syn:anti. Enolates derived from Me bromoacetate undergo deprotonation with LDA in the presence of indium trichloride followed by addition to aldehydes R1CHO [R1 = Ph, Me(CH2)6, (E)-PhCH:CH] or acetophenone to give epoxy esters such as I [R = H, Me; R1 = Ph, Me(CH2)6, (E)-PhCH:CH] in 23-80% yields with selectivities of 52:48 to 82:18 for the trans-epoxide stereoisomers. Phenacyl bromide undergoes self-condensation in the presence of indium trichloride under the standard coupling conditions; when lithium dicyclohexylamide was added to benzaldehyde, phenacyl chloride, and indium trichloride in THF, the Darzens condensation product was isolated solely as the trans stereoisomer in 77% yield.
Perkin 1 published new progress about 5340-78-3. 5340-78-3 belongs to esters-buliding-blocks, auxiliary class Aliphatic Chain, name is Ethyltert-butylacetate, and the molecular formula is C8H16O2, Synthetic Route of 5340-78-3.
Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics