Decrease of inorganic blood sulfate following treatment with selected antirheumatic drugs: potential consequence for articular cartilage was written by De Vries, B. J.;Van der Kraan, P. M.;Van den Berg, W. B.. And the article was included in Agents and Actions in 1990.Reference of 5003-48-5 The following contents are mentioned in the article:
The elimination kinetics of inorganic blood sulfate in mice was followed for 4 h after a single, oral administration of an antirheumatic drug. Sodium salicylate, aspirin, diflunisal, and benorylate, all in a dose of 1.25 mmol/kg, reduced the sulfate level to less than half that of control. This phenomenon was also demonstrated by phenylbutazone, oxyphenbutazone (both 1 mmol/kg), chloroquine diphosphate (0.6 mmol/kg), and tiaprofenic acid (0.02-0.35 mmol/kg). Niflumic acid (1.08 mmol/kg), piroxicam (0.03 mmol/kg), indomethacin (6.10-3 mmol/kg), diclofenac (5.10-3 mmol/kg), ketoprofen (0.2 mmol/kg), naproxen (0.08 mmol/kg), and ibuprofen (0.24 mmol/kg) possessed no sulfate-lowering properties. The potential relevance of the use of sulfate-lowering drugs for articular cartilage integrity is discussed. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5Reference of 5003-48-5).
4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Reference of 5003-48-5
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