Li, Xin published the artcileEnantio- and diastereoselective diarylmethylation of 1,3-dicarbonyl compounds, Recommanded Product: 3-Acetyldihydrofuran-2(3H)-one, the publication is Chemical Science (2020), 11(23), 5969-5973, database is CAplus and MEDLINE.
A Cu-catalyzed enantio- and diastereoselective diarylmethylation of 1,3-dicarbonyl compounds RC(O)CH(R1)C(O)R2 (R = Et, 4-methoxyphenyl, cyclohexyl, thiophen-2-yl, etc.; R1 = H, Me; R2 = Me, OMe, OEt, O(i-Pr); RR1 = -(CH2)3-, -(CH2)4-, -(CH2)2O-) and Me 1-oxo-2-indancarboxylate is described. It is a successful example of constructing all-carbon quaternary stereocenters from 3°C-H nucleophiles, a challenging topic in synthetic chem. In the present work, two contiguous stereocenters I (R3 = R4 = Me, t-Bu, i-Pr, TMS, Ph; R3 = Me, R4 = t-Bu; Ar = naphthalen-2-yl, 1-benzofuran-2-yl, 2,3-dihydro-1,4-benzodioxin-6-yl, thiophen-2-yl, etc.) are constructed with high levels of stereoselectivity and atom economy. The broad scope of 1,3-dicarbonyl nucleophiles and the tolerance of a wide range of functional groups make this protocol of great importance in the synthesis of chiral diarylmethane compounds I.
Chemical Science published new progress about 517-23-7. 517-23-7 belongs to esters-buliding-blocks, auxiliary class Tetrahydrofuran,Ketone,Ester, name is 3-Acetyldihydrofuran-2(3H)-one, and the molecular formula is C6H8O3, Recommanded Product: 3-Acetyldihydrofuran-2(3H)-one.
Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics