Garrido-Gonzalez, Jose J. published the artcileAn Enzyme Model Which Mimics Chymotrypsin and N-Terminal Hydrolases, SDS of cas: 1877-71-0, the publication is ACS Catalysis (2020), 10(19), 11162-11170, database is CAplus.
Enzymes are the most efficient and specific catalysts to date. Although they have been thoroughly studied for years, building a true enzyme mimic remains a challenging and necessary task. Here, we show how a three-dimensional geometry anal. of the key catalytic residues in natural hydrolases has been exploited to design and synthesize small-mol. artificial enzymes which mimic the active centers of chymotrypsin and N-terminal hydrolases. The optimized prototype catalyzes the methanolysis of the acyl enzyme mimic with a half-life of only 3.7 min at 20 °C, and it is also able to perform the transesterification of vinyl acetate at room temperature DFT studies and X-ray diffraction anal. of the catalyst bound to a transition state analog proves the similarity with the geometry of natural hydrolases.
ACS Catalysis published new progress about 1877-71-0. 1877-71-0 belongs to esters-buliding-blocks, auxiliary class Carboxylic acid,Benzene,Ester, name is 3-(Methoxycarbonyl)benzoic acid, and the molecular formula is C9H8O4, SDS of cas: 1877-71-0.
Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics