Month: November 2022

Van Lijsebetten, Filip; De Bruycker, Kevin; Spiesschaert, Yann; Winne, Johan M.; Du Prez, Filip E. published the artcile< Suppressing Creep and Promoting Fast Reprocessing of Vitrimers with Reversibly Trapped Amines>, Related Products of 112-63-0, the main research area is vitrimer amine polymer network creep; Creep-Resistance; Recyclable Thermoset; Transamination; Vinylogous Urethane; Vitrimers.

We report a straightforward chem. strategy to tackle current challenges of irreversible deformation in low Tg vitrimers at operating temperature In particular, vinylogous urethane (VU) vitrimers were prepared where reactive free amines, necessary for material flow, were temporarily shielded inside the network backbone, by adding a small amount of dibasic ester to the curing mixture The amines could be released as reactive chain ends from the resulting dicarboxamide bonds via thermally reversible cyclisation to an imide moiety. Indeed, (re)generation of the required nucleophilic amines as network defects ensured reprocessing and rapid material flow at higher temperature, where exchange dynamics are (re)activated. As a result, VU vitrimers were obtained with limited creep at service temperature, yet with good reprocessability at elevated temperatures Thus, by exerting strong control on the mol. level over the availability of exchangeable functional groups, a remarkable improvement of VU properties was obtained.

Angewandte Chemie, International Edition published new progress about Activation energy. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Related Products of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Westerhaus, Felix A.; Sorribes, Ivan; Wienhoefer, Gerrit; Junge, Kathrin; Beller, Matthias published the artcile< Reduction of Nitroarenes Using CO and H2O in the Presence of a Nanostructured Cobalt Oxide/Nitrogen-Doped Graphene (NGr) Catalyst>, Quality Control of 112-63-0, the main research area is cobalt oxide nitrogen doped graphene catalyst reduction nitroarene; carbon monoxide water reduction nitroarene; aromatic amine preparation.

The most common route to anilines is based on the reduction of the corresponding nitroarenes. In general, hydrogen is the preferred reducing agent and numerous catalytic systems are known to achieve such transformations. Besides, the use of CO/H2O as a hydrogen source offers interesting possibilities for reductions Carbon monoxide is a cheap and abundant chem. used on an industrial scale for a variety of transformations. Although the reduction of nitroarenes with CO/H2O is known in the presence of noble-metal catalysts, earth-abundant inexpensive catalysts showing high selectivity have not yet been developed. In this respect, herein we present the use of a heterogeneous cobalt oxide catalyst (Co3O4/NGr@C), which is modified by nitrogen-doped graphene layers. Using this non-noble metal catalyst, nitroarenes are reduced in high yields and good chemoselectivities.

Synlett published new progress about Aromatic amines Role: SPN (Synthetic Preparation), PREP (Preparation). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Quality Control of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Hazim, Roni A.; Paniagua, Antonio E.; Tang, Lisa; Yang, Krista; Kim, Kristen K. O.; Stiles, Linsey; Divakaruni, Ajit S.; Williams, David S. published the artcile< Vitamin B3, nicotinamide, enhances mitochondrial metabolism to promote differentiation of the retinal pigment epithelium>, Reference of 112-63-0, the main research area is retinal pigment epithelium vitamin B3 mitochondrial metabolism; RPE; differentiation; mitochondria; nicotinamide; retina.

In the mammalian retina, a metabolic ecosystem exists in which photoreceptors acquire glucose from the choriocapillaris with the help of the retinal pigment epithelium (RPE). While the photoreceptor cells are primarily glycolytic, exhibiting Warburg-like metabolism, the RPE is reliant on mitochondrial respiration. However, the ways in which mitochondrial metabolism affect RPE cellular functions are not clear. We first used the human RPE cell line, ARPE-19, to examine mitochondrial metabolism in the context of cellular differentiation. We show that nicotinamide induced rapid differentiation of ARPE-19 cells, which was reversed by removal of supplemental nicotinamide. During the nicotinamide-induced differentiation, we observed using quant. PCR, Western blotting, electron microscopy, and metabolic respiration and tracing assays that (1) mitochondrial gene and protein expression increased, (2) mitochondria became larger with more tightly folded cristae, and (3) mitochondrial metabolism was enhanced. In addition, we show that primary cultures of human fetal RPE cells responded similarly in the presence of nicotinamide. Furthermore, disruption of mitochondrial oxidation of pyruvate attenuated the nicotinamide-induced differentiation of the RPE cells. Together, our results demonstrate a remarkable effect of nicotinamide on RPE metabolism We also identify mitochondrial respiration as a key contributor to the differentiated state of the RPE and thus to many of the RPE functions that are essential for retinal health and photoreception.

Journal of Biological Chemistry published new progress about Animal gene Role: BSU (Biological Study, Unclassified), BIOL (Biological Study) (ATP5G1). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Reference of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Wang, Yutong; Xie, Jianchun; Zhang, Chenping; Xu, Yuxia; Yang, Xuelian published the artcile< Effect of lipid on formation of Maillard and lipid-Maillard meaty flavor compounds in heated cysteine-xylose-methyl linoleate system>, Application of C19H34O2, the main research area is cysteine xylose methyl linoleate lipid Maillard meaty flavor compound.

The effect of lipid level and reaction temperature and time on the heated cysteine-xylose reaction to form meaty flavors was investigated. The presence of 1% or 2% Me linoleate inhibited the formation of volatile sulfur-containing compounds and heterocyclic compounds via the Maillard reaction, that is Maillard compounds However, the former was better because of the moderate inhibition and more compounds generated from the lipid-Maillard interaction, that is lipid-Maillard compounds Partial least squares-discriminant anal. suggested the lipid-Maillard compounds were the main markers during varying dosage of Me linoleate, reaction temperature (100-140°C) and reaction time (30-180 min). Lower temperatures increased formation of the Maillard compounds (eg, 2-furfurylthiol) or lipid-Maillard compounds (eg, 2-pentylpyridine) with reaction time. However, high temperatures caused their amounts changed in a curve or irregularly due to the complications from the Maillard and lipid oxidization reactions. By comparing time-courses of the levels of cysteine and Cys-Amadori compounds, and 294 and 420 nm UV absorbance values in the reaction systems under 120°C with or without 2% Me linoleate, it was revealed that the underlying lipid effect mechanism was to initially inhibit and later attend the Maillard reaction, leading to less formation of the Maillard compounds and generation of the lipid-Maillard compounds

Flavour and Fragrance Journal published new progress about Heterocyclic compounds Role: TEM (Technical or Engineered Material Use), USES (Uses). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Application of C19H34O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Arnold, Rachelle M.; Sheppard, Gareth R.; Locklin, Jason published the artcile< Comparative Aminolysis Kinetics of Different Active Ester Polymer Brush Platforms in Postpolymerization Modification with Primary and Aromatic Amines>, COA of Formula: C9H3F5O2, the main research area is aminolysis kinetics active ester polymer brush postpolymn modification.

The kinetics of aminolysis between two different active ester polymer brush platforms, poly(4-pentafluorophenyl acrylate) (poly(PFPA)) and poly(N-hydroxysuccinimide-4-vinyl benzoate) (poly(NHS4VB)), are compared using primary and aromatic amines with varying reactivity toward postpolymn. modification. UV-vis was used to monitor the aminolysis of both brush platforms with 1-aminomethylpyrene (AMP), 1-aminopyrene (AP), and Ru(bpy)2(phen-5-NH2)(PF6) (Ru2+A). Using a pseudo-first-order kinetics model, the pseudo-first-order rate constant (k’) was calculated for each system. The k’ of poly(PFPA) modified with AMP, AP, and Ru2+A were 2.46 × 10-1, 5.11 × 10-3, and 2.59 × 10-3 s-1, resp., while poly(NHS4VB) can only be functionalized with the alkyl amine, albeit at a slower rate constant, k’ of 3.49 × 10-3 s-1, compared to that of poly(PFPA) with AMP. The kinetics of surface-initiated photopolymerization of PFPA from oxide surfaces was also studied as an effective method to control grafting d. and film thickness.

Macromolecules (Washington, DC, United States) published new progress about Aminolysis kinetics. 71195-85-2 belongs to class esters-buliding-blocks, and the molecular formula is C9H3F5O2, COA of Formula: C9H3F5O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Pattenden, Gerald; Critcher, Douglas J.; Remuinan, Modesto published the artcile< Total synthesis of (-)-pateamine A, a novel immunosuppressive agent from Mycale sp>, Safety of (S)-Dimethyl 2-hydroxysuccinate, the main research area is asym synthesis pateamine A Stille coupling reaction; sulfinimine chiral auxiliary beta amino ester preparation pateamine A.

A convergent synthesis of the unique thiazole-containing polyene bis-lactone pateamine A (I) isolated from the marine sponge Mycale sp is described. The synthesis features the ubiquitous Stille sp2-sp2 coupling reaction to elaborate the E,Z-diene macrolide core and the all-E polyenamine side chain in the natural product. It also highlights the scope for enantiopure sulfinimine intermediates in the synthesis of chiral β-amino ester moieties in complex structures.

Canadian Journal of Chemistry published new progress about Chiral auxiliary. 617-55-0 belongs to class esters-buliding-blocks, and the molecular formula is C6H10O5, Safety of (S)-Dimethyl 2-hydroxysuccinate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Huynh, Man P.; Hibbard, Bruce E.; Ho, Khanh-Van; Shelby, Kent S. published the artcile< Toxicometabolomic profiling of resistant and susceptible western corn rootworm larvae feeding on Bt maize seedlings>, Product Details of C19H34O2, the main research area is Zea Diabrotica larva seedling toxicometabolomics.

The western corn rootworm (WCR), Diabrotica virgifera virgifera LeConte, is the most serious pest of maize (Zea mays L.) in the U. S. Corn Belt and parts of Europe. Transgenic maize hybrids expressing at least one of the four currently available insecticidal toxins from Bacillus thuringiensis (Bt) Berliner, currently the most widely adopted control method in continuous maize, have faltered due to the emergence of resistance. The resistance mechanisms of WCR to Bt toxins are not fully understood. We identified metabolic profiles of susceptible and resistant WCR larvae fed on maize hybrids expressing each of three available Cry3 proteins (eCry3Ab1, mCry3A, and Cry3Bb1) targeting corn rootworms and a control non-Bt maize via an untargeted metabolomics approach. Over 580 unique metabolites found in WCR larvae were classified into different pathways (amino acids, carbohydrates, cofactors and vitamins, energy, lipid, nucleotide, peptide, and xenobiotics). By exploring shifts in WCR larval metabolome exclusively by Bt toxins, several candidate metabolites and metabolic pathways were identified in susceptible and resistant larvae that may be involved in defense against or recovery from Bt ingestion by these larvae. These findings would provide mechanistic insights into altered metabolic pathways associated with the resistance mechanisms of WCR to Bt toxins.

Scientific Reports published new progress about Amino acids Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Product Details of C19H34O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Bhavani, R.; Rathinavel, P. published the artcile< Evaluation of phytochemical profile and in vitro antioxidant properties of Terminalia chebula fruits>, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is Terminalia chebula fruit phytochem antioxidant property.

The fruit of Terminalia chebula have wide applications in folk medicine since ancient times due to the presence of several bioactive compounds This study aims at the anti-oxidant capacity and the screening of phytochems. from the fruits of the T. chebula. Preliminary phytochem. screening of leaf showed the presence of Carbohydrates, protein, steroids, glycosides, tannins, flavonoids, alkaloids, saponin, starch, terpenoids, anthrocyanin, coumarin, phytosterol, glycosides and chalcogens in the different extracts The ethanol, aqueous and chloroform extracts of the fruit were tested for antioxidant activity using scavenging activities of DPPH radical, Nitric oxide, reducing power, hydrogen peroxide and superoxide methods. Among the three different extracts tested, the ethanol extract has registered noticeable effect in all scavenging assays than other extracts tested. The finding suggests that the three different extracts of T. chebula fruit showed different level of antioxidant activity and it is potential source of natural antioxidants.

International Journal of Current Research in Chemistry and Pharmaceutical Sciences published new progress about Alkaloids Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Geahlen, Robert L.; Loudon, G. Marc; Paige, Lisa A.; Lloyd, David published the artcile< A general method for preparation of peptides biotinylated at the carboxy terminus>, HPLC of Formula: 112-63-0, the main research area is biotinylated peptide C terminus; Merrifield synthesis biotinylated peptide.

A method for the preparation of a biotinylated resin that can be elongated by standard methods of solid-phase peptide synthesis to give peptides biotinylated at the carboxy terminus is described. This methodol. is particularly important for the preparation of biotinylated peptides in which a free amino terminus is required. Coupling of Nε-9-fluorenylmethoxycarbonyl(Fmoc)-Nα-tert-butyloxycarbonyl(Boc)-L-lysine to p-methylbenzhydrylamine resin, followed by removal of the Fmoc protecting group and reaction with (+)-biotin-4-nitrophenyl ester yielded Nα-Boc-biocytin-p-methylbenzhydrylamine resin. The utility of this resin was tested by the synthesis of a biotinylated peptide, Gly-Asn-Ala-Ala-Ala-Ala-Arg-Arg-biocytin-NH2, for use as an in vitro substrate for myristoyl-CoA:protein N-myristoyltransferase (NMT), the enzyme that catalyzes protein N-myristoylation. Anal. of the peptide derivative by HPLC and mass spectrometry revealed a single major product of the expected mass, indicating that the biotin group survived cleavage and deprotection with HF. The biotinylated peptide served as a substrate for NMT, and the resulting myristoylated peptide could be quant. recovered by adsorption to immobilized avidin.

Analytical Biochemistry published new progress about Peptides Role: SPN (Synthetic Preparation), PREP (Preparation). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, HPLC of Formula: 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Dawood, Sumreen; Ahmad, Mushtaq; Zafar, Muhammad; Asif, Saira; Klemes, Jiri Jaromir; Bokhari, Awais; Mubashir, Muhammad; Han, Ning; Ibrahim, Mohamed M.; El-Bahy, Zeinhom M.; Khoo, Kuan Shiong published the artcile< Biodiesel synthesis from Prunus bokhariensis non-edible seed oil by using green silver oxide nanocatalyst>, Application In Synthesis of 112-63-0, the main research area is Prunus nonedible seed silver oxide nanocatalyst biodiesel oil; Green nanocatalyst; Non edible oil; Prunus bokhariensis, transesterification; Silver oxide.

The present work investigates the proficiency of green silver oxide nanocatalyst synthesized from Monotheca buxifolia (Falc.) Dcne. leaves extract, and their application for biodiesel synthesis from novel Prunus bokhariensis seed oil (non-edible). The seed oil content of 55% and FFA content of 0.80 mg KOH/g were reported. Several anal. tools (EDX, FT-IR, SEM and XRD) were used to characterize the Ag2O nanocatalyst. Maximum (89%) FAME yield of the PBSOB (Prunus bokhariensis seed oil biodiesel) was achieved at ambient transesterification conditions i.e. 3.5 wt% nanocatalyst loading, 2.5 h reaction time, 130°C of reaction temperature and 12:1 alc. to oil ratio. The synthesized PBSOB was addnl. characterised by anal. methods like, GC-MS and FT-IR. The different aspects of fuel were identified i.e. flash point (84°C), kinematic viscosity (4.01 cSt @ 40°C), sulfur content (0.0003 wt %), d. (0.853 kg/L) and acid number (0.167 mg KOH/g). All the above properties were verified and agreed well with biodiesel international standards (European Union (14214)), China GB/T (20828) and ASTM (6751, 951). In general, Prunus bokhariensis seed oil and Ag2O nanocatalyst seem to be remarkably active, cheap and stable candidates for the biodiesel industry in future.

Chemosphere published new progress about Biodiesel fuel. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Application In Synthesis of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics