Month: November 2022

Zhao, Haiwei; Herbert, Simon; Kinzel, Tom; Zhang, Wei; Shen, Qilong published the artcile< Two Ligands Transfer from Ag to Pd: En Route to (SIPr)Pd(CF2H)(X) and Its Application in One-Pot C-H Borylation/Difluoromethylation>, Application of C9H7F3O2, the main research area is fluoromethyl palladium imidazolinylidene complex preparation crystal structure fluoromethylation catalyst; crystal structure fluoromethyl palladium arylimidazolinylidene complex; mol structure fluoromethyl palladium arylimidazolinylidene complex; hetero arene borylation difluoromethylation palladium catalyst; fluoromethylated heteroarene preparation.

A process for the concurrent transfer of both the NHC ligand and difluoromethyl group from [(SIPr)Ag(CF2H)] to PdX2 (X = Cl, OAc and OPiv) for the preparation [(SIPr)Pd(CF2H)X] complexes is described. These complexes were air-stable and easily underwent transmetalation with aryl pinacol boronate/reductive elimination to generate ArCF2H in high yields. Based on this discovery, the 1st 1-pot C-H borylation and difluoromethylation for the preparation of difluoromethylated (hetero)arenes was developed.

Journal of Organic Chemistry published new progress about Aromatic hydrocarbons Role: RCT (Reactant), RACT (Reactant or Reagent). 2557-13-3 belongs to class esters-buliding-blocks, and the molecular formula is C9H7F3O2, Application of C9H7F3O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Yang, Rong; Gu, Guozhang; Tang, Chen; Miao, Zhicheng; Cao, Hongwei; Zou, Guoxiang; Li, Jinchun published the artcile< Super-tough and flame-retardant poly(lactic acid) materials using a phosphorus-containing malic acid-based copolyester by reactive blending>, Recommanded Product: (S)-Dimethyl 2-hydroxysuccinate, the main research area is fireproofing polylactic phosphorus malic polyester reactive blending.

It is a great challenge to simultaneously prepare flame-retardant and super-tough poly(lactic acid) (PLA) materials. Herein, we reported a facile approach that PLA reactively blends with phosphorus-containing copolyester. In this paper, a quinary aliphatic copolyester (PPE) containing phosphorus and pendent hydroxyl group was synthesized with sebacic acid, di-Me malate, di-Et phosphite, 1,6-hexanediol, and 1,3-propanediol by polycondensation. Then, flame-retardant and super-tough PLA materials (PLA/PPEU) can be achieved by reactively blending with PPE and hexamethylene diisocyanate. The results showed that the toughness of PLA was significantly enhanced. The maximum notched impact strength is 75.3 kJ/m2 indicated a super toughness performance. Meanwhile, the flame retardance of the PLA was improved obviously. The limited oxygen index (LOI) of PLA increased from 20 to 26%. Moreover, the PLA blends can pass the UL-94 V-0 rating. In addition, both the total heat release and total smoke production of PLA were decreased. The resultant super-tough and flame-retardant PLA materials could be widely applied in elec. and electronic equipment.

Polymer Degradation and Stability published new progress about Chars. 617-55-0 belongs to class esters-buliding-blocks, and the molecular formula is C6H10O5, Recommanded Product: (S)-Dimethyl 2-hydroxysuccinate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Yu, Jin-Sheng; Zhou, Feng; Liu, Yun-Lin; Zhou, Jian published the artcile< Organocatalytic asymmetric Michael addition of unprotected 3-substituted oxindoles to 1,4-naphthoquinone>, HPLC of Formula: 112-63-0, the main research area is indole quaternary stereogenic center preparation enantioselective synthesis; organocatalyst asym Michael addition oxindole naphthoquinone; 3,3-disubstituted oxindoles; Michael addition; organocatalysis; quaternary stereogenic center; unprotected 3-substituted oxindoles.

The authors reported the first example of an organocatalytic Michael addition of unprotected 3-prochiral oxindole derivatives to 1,4-naphthoquinone. A quinidine derivative (DHQD)2PYR was found to catalyze this reaction in up to 83% ee, with moderate to excellent yields. This method could be used for the synthesis of enantioenriched 3,3-diaryloxindole derivatives, the catalytic synthesis of which was unprecedented. The synthesis of the target compound was achieved using 1,3-dihydro-2H-indol-2-one derivatives and 1,4-naphthalenedione as starting materials. The title compounds thus formed included a 2-(2-oxo-3-indolyl)-1,4-naphthalenedione derivative (I) and related substances.

Beilstein Journal of Organic Chemistry published new progress about Enantioselective synthesis. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, HPLC of Formula: 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Tsuboi, Ririko; Kitagawa, Haruaki; Imazato, Satoshi published the artcile< FGF-2 release and bonding/physical properties of 4-META/MMA-based adhesive resins incorporating small FGF-2-loaded polymer particles>, Formula: C18H26O6, the main research area is adhesive resin incorporating small FGF loaded polymer particle; Adhesive resin; FGF-2; Mechanical property; Osteoblast-like cell; polyHEMA/TMPT.

Non-biodegradable particles comprising hydroxyethyl methacrylate (HEMA) and trimethylolpropane trimethacrylate (TMPT) have been reported as useful carriers for fibroblast growth factor-2 (FGF-2). They have also been successfully incorporated into the 4-[2-(methacryloyloxy)ethoxycarbonyl]phthalic anhydride/methyl methacrylate-tri-Bu borane (4-META/MMA-TBB) resin to promote tissue regeneration. However, smaller particles are required to obtain restorative materials acceptable for clin. use. The aim of this study was to investigate the ability of the 4-META/MMA-TBB resin that comprises small FGF-2-loaded particles to release FGF-2 and promote cell proliferation. In addition, the bonding and phys. properties of the exptl. resin were evaluated.The small particles loaded with FGF-2 were newly fabricated and incorporated into the com. 4-META/MMA-TBB resin. Release profiles of FGF-2 from the exptl. resins were assessed, and the cell proliferation cultured with the eluate was evaluated. The bonding and phys. properties of the resins were evaluated using shear bond strength and three-point bending tests, and by measuring the curing time, water absorption, and water dissolutionSustained release of FGF-2 from the exptl. resins for two weeks was observed, and the released FGF-2 was demonstrated to promote cell proliferation. All bonding and phys. properties of the 4-META/MMA-TBB resins were found acceptable for clin. use.The small FGF-2-loaded particles incorporated into the 4-META/MMA-TBB resin had the same abilities to release FGF-2 and proliferate cells, as those exhibited by the conventionally sized particles. In addition, there were no adverse influences on bonding and phys. properties, suggesting that the bioactive adhesive resin was acceptable for clin. use.

Dental Materials published new progress about Absorption. 3290-92-4 belongs to class esters-buliding-blocks, and the molecular formula is C18H26O6, Formula: C18H26O6.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Husstedt, Urda; Schaefer, Hans J. published the artcile< Retention of configuration in double bond protection-deprotection by bromination-cathodic debromination>, Application of C19H34O2, the main research area is double bond protection configuration; bromination debromination double bond protection.

The double bond functionality of unsaturated carboxylic acids and alcs. was protected by bromination with pyridinium hydrobromide perbromide under mild conditions. Deprotection was achieved by cathodic reduction at -1.4 V. Overall yields of 68-99% were obtained and the configuration of the double bond was retained by ≥96%.

Tetrahedron Letters published new progress about Alcohols, unsaturated Role: RCT (Reactant), RACT (Reactant or Reagent). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Application of C19H34O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Njeri, Dancan K.; Pertuit, Claude J.; Ragains, Justin R. published the artcile< 1,2-cis-Selective glucosylation enabled by halogenated benzyl protecting groups>, Name: Benzyl (3-hydroxypropyl)carbamate, the main research area is disaccharide thioglycoside stereoselective glycosylation preparation uronate cholesterol; Williamson etherification stereoselective glycosylation protecting group glucosylation thioglucoside trichloroacetimidate.

We report on our initial results from a systematic effort to implement electron-withdrawing protecting groups and Lewis basic solvents/additives as an approach to 1,2-cis(α)-selective O-glucosylation. 1,2-cis-Selective O-glucosylation are reported with thioglucosides and glucosyl trichloroacetimidates and a range of acceptors. A correlation between electron-withdrawing effects and 1,2-cis selectivity has been established. This phenomenon may prove to be broadly applicable in the area of chem. O-glycosylation.

Organic & Biomolecular Chemistry published new progress about Disaccharides Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 34637-22-4 belongs to class esters-buliding-blocks, and the molecular formula is C11H15NO3, Name: Benzyl (3-hydroxypropyl)carbamate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Tang, Feiyu; Shao, Deyi; Chen, Gong; Luo, Haihua published the artcile< Osmotic components in cotton (Gossypium Hirsutum L.) fibers in response to soil moisture deficit during fiber expansion>, Synthetic Route of 112-63-0, the main research area is Gossypium Hirsutum fiber expansion soil moisture deficit.

The present study aimed to determine how main osmotic active substances (malate, potassium and soluble sugars) in cotton fibers respond to soil drought. A pot study with two water regimes was performed in 2015 and 2016 using two cotton lines A001 and A705. The irrigated plants (control) were watered at 1-d interval with the optimum quantity of underground water determined on the basis of a gravimetric method. Drought treatment was defined as withdrawing water from pots until the leaf wilting symptom was visible, and water stressed plants were exposed to limited water supply for 25 days receiving 50% of the control irrigation at 2-d interval. Following 25 days of water deficit treatment, those plants were re-watered with the same quantity as the control. Drought induction caused a significant reduction in fiber length and strength in A001. Net photosynthetic rate (Pn), stomatal conductance (gs), and transpiration rate (E) in A001 and A705 were reduced significantly by soil drought indicating the present water deficit design did generate a photosynthetically physiol. difference. The depressed leaf photosynthesis led to the deficient accumulation of soluble sugars, malate and potassium in water stressed fibers, and in turn to the reduced fiber length.

Pakistan Journal of Botany published new progress about Bioaccumulation. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Synthetic Route of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Singh, Yashvir; Sharma, Abhishek; Singh, Nishant Kumar; Chen, Wei-Hsin published the artcile< Development of bio-based lubricant from modified desert date oil (balanites aegyptiaca) with copper nanoparticles addition and their tribological analysis>, Name: (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is lubricant modified desert date oil copper nanoparticles.

Based on the environmental concerns related to the pollution caused by the vehicles and the demand for an alternative to the conventional lubricant resulted in the studies to be conducted that are environmental-friendly. In this study, friction and wear behavior of the surfaces in contact was conducted to observe their tendency during the application of an alternative lubricant to the mineral oil. Desert date oil was having the potential of an alternative to the mineral oil and they were available in abundant amount During the initial stage, desert date oil was transesterified using the two-step transesterification process and further it was added to the trimethylolpropane. After this process, nanoparticles were added in different amounts to the modified desert date oil. The friction and wear behavior of the modified desert date oil was tested using four-ball tester under different conditions. For the surface topog. anal., SEM and EDS anal. were conducted. The concentration of the nanoparticles added to the biolubricant was considered based on the previous work conducted. The input parameters which were considered during the test consists of normal load, sliding speed, variation in the addition of the nanoparticles to the biolubricant (0.3-1.6% with a gap of 0.3%). Based on the study conducted, 0.9% concentration of the copper nanoparticles showed a significant improvement in term of reducing COF, wear rate, mean wear scar diameter and improved worn surface morphol. was obtained with comparison to the mineral oil. The maximum increment in the properties relative to the tribol. anal. was shown when the concentration of the copper nanoparticles to the modified desert date oil increases beyond 0.9% copper nanoparticles during the addition in the amount of 1.3% and 1.6%. Conclusively, the performance of the modified desert date oil with 0.9% copper nanoparticles addition has the potential impact as a lubricant with comparison to the mineral oil and other samples. The modified desert date oil with an application of 0.9% copper nanoparticles could be considered as a suitable alternative to the mineral oil while considering environmental concern and energy saving.

Fuel published new progress about Balanites aegyptiaca. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Name: (9Z,12Z)-Methyl octadeca-9,12-dienoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Zhdanov, A. K. published the artcile< The heat capacities of some pure liquids and azeotropic mixtures>, Application of C19H34O2, the main research area is .

Measurements of the heat capacities (Cp) were made for CCl4, PrOH, benzene, iso-BuOH, PhMe and the azeotropic mixtures: benzene-MeCOEt, PhMe-iso-AmOH, benzene-PrOH, CCl4-PrOH, CCl4-iso-BuOH, PhMe-PrOH, CCl4-iso-BuOH and PhMe-iso-BuOH at 4.5-6°, 24-5° and 44.5-47.2°. The deviations of results were ± 0.001 and the exptl. errors of the Cp values did not exceed 0.5%. Interpolation equations of the type Cp = A + BT + CT2 were also obtained. The following values were obtained for CCl4 at 278.68, 298.01 and 319.28°, resp.: Cp 0.2013, 0.2053 and 0.2095. For PrOH the corresponding values at 279.66, 290.76, 297.57, 304.06 and 318.83° were Cp 0.5431, 0.5623, 0.5781, 0.5951 and 0.6480. For iso-BuOH at 278.34, 296.35 and 319.01° the values were Cp 0.5322, 0.5916 and 0.6600. For benzene at 281.38, 295.61 and 318.81° the values were Cp 0.4044, 0.4141 and 0.4316. For PhMe at 278.51, 296.80 and 320.42° the values were Cp 0.3871, 0.4077 and 0.4312. For the azeotropic mixture benzene (62.5%)-MeCOEt (37.5%) at 278.33, 298.27 and 318.8° the values were Cp 0.4390, 0.4587 and 0.4787. For PhMe (86%)-iso-AmOH (14%) at 278.25, 289.56, 305.36 and 319.77° the values were, resp., Cp 0.4328, 0.4147, 0.4647 and 0.4777. For benzene (83.1%)-PrOH (16.9%) at 278.43, 297.59 and 318.88° the values were, resp., Cp 0.4623, 0.4908 and 0.5115. For CCl4 (88.5%)-PrOH (1.5%) at 278.86, 297.04 and 319.65° the values were Cp 0.2523, 0.2681 and 0.2781. For CCl4 (82%)-iso-PrOH (18%) at 278.26, 296.65 and 320.12° the values were Cp 0.2814, 0.3003 and 0.3316. For PhMe (47.5%)-PrOH (52.5%) at 278.44, 296.09 and 318.41° the values were Cp 0.5041, 0.5365 and 0.5787. For PhMe (55.5%)-iso-BuOH (45.5%) at 278.62, 295.34 and 317.75° the values were Cp 0.4987, 0.5223 and 0.5667. For CCl4 (94.5%)-iso-BuOH (5.5%) at 278.56, 298.77 and 319.60° the values were Cp 0.2320, 0.2462 and 0.2540. The values of A, B × 102 and C × 104 in the interpolation equation and the value k1 × 106 for the equation MCpe = k1Te3 are, resp., CCl4, 22.32, 3.103, – and 0.78; PrOH 176.34, -110.5483, 21.1542 and 1.12; iso-BuOH -25.31, 23.26, – and 1.14; benzene 18.45, 3.5627, 0.3813 and 0.81; PhMe 8.42, 9.76, – and 0.82; benzene-PrOH -75.06, 65.699, -9.4844 and 0.94; benzene-MeCOEt 12.56, 7.428, – and 0.89; PhMe-iso-AmOH 12.12, 9.875, – and 0.89; CCl4-PrOH -111.20, 89.5549, 13.5827 and 0.93; CCl4-iso-PrOH 71.85, -38.0897, 8.7729 and 1.07; CCl4-iso-BuOH -90.26, 76.4934, -11.4848 and 0.93; PhMe-PrOH 7.65, 7.5249, 0.9889 and 1.00; PhMe-iso-BuOH 108.42, -57.7821, 12.1092 and 1.15. Four references.

Zhurnal Obshchei Khimii published new progress about Azeotropes. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Application of C19H34O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Ma, Zhiwei; Liu, Zhijing; Wang, Chuanchuan; Chen, Xiaopei; Tao, Jingchao; Lv, Quanjian published the artcile< A novel isosteviol-based bifunctional squaramide organocatalyst for enantioselective Michael addition of acetylacetone to nitroolefins>, Category: esters-buliding-blocks, the main research area is nitroalkane preparation enantioselective; diketone nitroolefin Michael addition bifunctional squaramide catalyst; Michael addition; acetylacetone; nitroolefin; organocatalysis; tertiary amine-squaramide.

In this study, novel chiral tertiary amine-squaramide I derived from the natural product of the stevioside was developed and applied into the asym. Michael addition of acetylacetones RC(O)CH2C(O)R1 (R = R1 = Me, Ph) to nitroolefins (E)-R2CH=CHNO2 (R2 = naphthalen-1-yl, 4-chlorophenyl, 2-furanyl, etc.). This asym. reaction performed well, and a series of enantiomerically enriched compounds (S/R)-RC(O)CH(CH(R2)CH2NO2)C(O)R1 were obtained in high yields (up to 96%) with excellent enantioselectivities (up to 99% ee).

Chirality published new progress about Alkanes, nitro Role: SPN (Synthetic Preparation), PREP (Preparation). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Category: esters-buliding-blocks.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics