Month: November 2022

Pratika, Remi Ayu; Wijaya, Karna; Trisunaryanti, Wega published the artcile< Hydrothermal treatment of SO4/TiO2 and TiO2/CaO as heterogeneous catalysts for the conversion of Jatropha oil into biodiesel>, Safety of (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is titania sulfur calcium oxide catalyst hydrothermal treatment Jatrophaoil biodiesel.

The conversion of Jatropha oil into biodiesel has been conducted using the SO4/TiO2 acid and TiO2/CaO base catalysts via hydrothermal treatment using an autoclave reactor. The acid catalyst was prepared with the sulfation process of TiO2 using H2SO4 (0.5; 0.8; 1.1; 1.4; 1.7 and 2 M). The base catalyst was initiated by dispersing TiO2 (1, 5, 10, 15, and 20 wt%) on CaO. The aims of this research were to obtain the catalyst with the highest acidity and basicity from SO4/TiO2 acid and TiO2/CaO catalysts, resp. Afterward, apply them to the esterification to reduce the free fatty acid of Jatropha oil and the transesterification of the esterified of Jatropha oil into biodiesel. Among the SO4/TiO2 catalysts, the ST-2-400 catalyst exhibits an optimum total acidity of 6.93 mmol NH3/g. This catalyst was able to reduce the FFA level of Jatropha oil from 1.22% to 0.59% with catalyst weight of 3%, ratio oil to methanol of 1:15, and reaction time of 90 min. The optimum total basicity from TiO2/CaO catalysts was achieved by TC-20-800 with the total basicity of 28.67 mmol HCl/g. The conversion of esterified Jatropha oil into biodiesel was performed using 3% of TC-20-800 catalyst at 65°C for 90 min. The TC-20-800 catalyst was able to produce biodiesel up to 79.68%.

Journal of Environmental Chemical Engineering published new progress about Acid number. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Safety of (9Z,12Z)-Methyl octadeca-9,12-dienoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Wimmer, Eric; Borghese, Sophie; Blanc, Aurelien; Beneteau, Valerie; Pale, Patrick published the artcile< Zeolite-Based Organic Synthesis (ZeoBOS) of Acortatarin A: First Total Synthesis Based on Native and Metal-Doped Zeolite-Catalyzed Steps>, Reference of 7126-50-3, the main research area is acortatarin A total synthesis zeolite organic synthesis; spiroketalization silver zeolite catalyst total synthesis acortatarin A; cross coupling copper zeolite catalyst total synthesis acortatarin A; copper; doped-zeolite; silver; spiroketalization; ynamide formation.

Similarly to polymer-supported assisted synthesis (PSAS), organic synthesis could be envisaged being performed by using zeolites, native or metal-doped, as heterogeneous catalysts. To illustrate this unprecedented Zeolite-Based Organic Synthesis (ZeoBOS), the total synthesis of acortatarin A (I) was achieved through a novel strategy and using five out of eleven synthetic steps catalyzed by H- or metal-doped zeolites as catalysts. Notably, the formation of an yne-pyrrole intermediate with a copper-doped zeolite and the spiroketalization of an alkyne diol with a silver-doped zeolite have been developed as key steps of the synthesis.

Chemistry – A European Journal published new progress about Cross-coupling reaction. 7126-50-3 belongs to class esters-buliding-blocks, and the molecular formula is C8H9NO3, Reference of 7126-50-3.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Critcher, Douglas; Pattenden, Gerald published the artcile< Synthetic studies towards pateamine, a novel thiazole-based 19-membered bis-lactone from Mycale sp>, Reference of 617-55-0, the main research area is pateamine lactone preparation.

A concise synthesis of the 19-membered bis-lactone core I present in pateamine using chiral pool starting materials and featuring an intramol. Stille coupling reaction as a key stratagem, is described.

Tetrahedron Letters published new progress about 617-55-0. 617-55-0 belongs to class esters-buliding-blocks, and the molecular formula is C6H10O5, Reference of 617-55-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Yao, Tianwen; Su, Wenxiang; Han, Shisheng; Lu, Yan; Xu, Yanqiu; Chen, Min; Wang, Yi published the artcile< Recent advances in traditional Chinese medicine for treatment of podocyte injury>, COA of Formula: C19H34O2, the main research area is review podocyte injury traditional Chinese medicine treatment; active ingredient; acupuncture and moxibustion; compound prescription; herbs; podocyte injury; traditional Chinese medicine.

A review. Podocyte is also called glomerular epithelial cell, which has been considered as the final gatekeeper of glomerular filtration barrier (GFB). As a major contributor to proteinuria, podocyte injury underlies a variety of glomerular diseases and becomes the challenge to patients and their families in general. At present, the therapeutic methods of podocyte injury mainly include angiotensin-converting enzyme inhibitors or angiotensin receptor blockers, steroid and immunosuppressive medications. Nevertheless, the higher cost and side effects seriously disturb patients with podocyte injury. Promisingly, traditional Chinese medicine (TCM) has received an increasing amount of attention from different countries in the treatment of podocyte injury by invigorating spleen and kidney, clearing heat and eliminating dampness, as well enriching qi and activating blood. Therefore, we searched articles published in peer-reviewed English-language journals through Google Scholar, PubMed, Web of Science, and Science Direct. The protective effects of active ingredients, herbs, compound prescriptions, acupuncture and moxibustion for treatment of podocyte injury were further summarized and analyzed. Meanwhile, we discussed feasible directions for future development, and analyzed existing deficiencies and shortcomings of TCM in the treatment of podocyte injury. In conclusion, this paper shows that TCM treatments can serve as promising auxiliary therapeutic methods for the treatment of podocyte injury.

Frontiers in Pharmacology published new progress about Abelmoschus manihot. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, COA of Formula: C19H34O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Foong, Choon Pin; Higuchi-Takeuchi, Mieko; Ohtawa, Kenji; Asai, Takuya; Liu, Hanqin; Ozeki, Yasuyuki; Numata, Keiji published the artcile< Engineered mutants of a marine photosynthetic purple nonsulfur bacterium with increased volumetric productivity of polyhydroxyalkanoate bioplastics>, Safety of (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is mutagenesis polyhydroxyalkanoate bioplastic Rhodovulum; Rhodovulum sulfidophilum; biopolymer; fluorescence-activated cell sorting; genome-wide mutagenesis; microbial cell factory; strain improvement.

Polyhydroxyalkanoates (PHAs) are green and sustainable bioplastics that could replace petrochem. synthetic plastics without posing environmental threats to living organisms. In addition, sustainable PHA production could be achieved using marine photosynthetic purple nonsulfur bacteria (PNSBs) that utilize natural seawater, sunlight, carbon dioxide gas, and nitrogen gas for growth. However, PHA production using marine photosynthetic PNSBs has not been economically feasible yet due to its high cost and low productivity. In this work, strain improvement, using genome-wide mutagenesis coupled with high-throughput screening via fluorescence-actived cell sorting, we were able to create Rhodovulum sulfidophilium mutants with enhanced volumetric PHA productivity, with an up to 1.7-fold increase. The best selected mutants (E6 and E6M4) reached the stationary growth phase 1 day faster and accumulated the maximum PHA content 2 days faster than the wild type. Maximizing volumetric PHA productivity before the stationary growth phase is indeed an addnl. advantage for R. sulfidophilum as a growth-associated PHA producer.

ACS Synthetic Biology published new progress about Bioplastics Role: BMF (Bioindustrial Manufacture), BIOL (Biological Study), PREP (Preparation). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Safety of (9Z,12Z)-Methyl octadeca-9,12-dienoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Tandon, Vishnu K.; Van Leusen, Albert M.; Wynberg, Hans published the artcile< Synthesis of enantiomerically pure (S)-(+)-3-hydroxytetrahydrofuran, and its (R)-enantiomer, from malic or tartaric acid>, Safety of (S)-Dimethyl 2-hydroxysuccinate, the main research area is furanol tetrahydro enantiomer; hydroxytetrahydrofuran enantiomer; butanetriol cyclodehydration.

The title compounds [(S)- and (R)-I] were prepared in high yield and high enantiomeric purity by cyclodehydration of (S)- and (R)-1,2,4-butanetriol, resp. Thus, (S)-HO2CCH(OH)CH2CO2H was esterified and reduced with LiAlH4 to give the (S)-triol, which was treated with 4-MeC6H4SO3H to give 87% (S)-I.

Journal of Organic Chemistry published new progress about Cyclization. 617-55-0 belongs to class esters-buliding-blocks, and the molecular formula is C6H10O5, Safety of (S)-Dimethyl 2-hydroxysuccinate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Alain, Valerie; Redoglia, Stephane; Blanchard-Desce, Mireille; Lebus, Sonja; Lukaszuk, Katarzyna; Wortmann, Rudiger; Gubler, Ulrich; Bosshard, Christian; Gunter, Peter published the artcile< Elongated push-pull diphenylpolyenes for nonlinear optics: molecular engineering of quadratic and cubic optical nonlinearities via tuning of intramolecular charge transfer>, Application of C19H34O2, the main research area is push pull diphenyl polyene nonlinear optic; intramol charge transfer push pull diphenyl polyene; dipole moment push pull diphenyl polyene; hyperpolarizability push pull diphenyl polyene.

Push-pull polyenes are of particular interest for nonlinear optics (NLO) as well as model compounds for long-distance intramol. charge transfer (ICT). In order to tune the ICT phenomenon and control the linear and nonlinear optical properties, we have synthesized and investigated several series of soluble push-pull diphenylpolyenes of increasing length and having various donor (D) and acceptor (A) end groups. Their linear and NLO properties have been studied by performing electro-optical absorption measurements (EOAM) and third-harmonic generation (THG) experiments in solution Each push-pull mol. exhibits an intense ICT absorption band in the visible characterized by an increase in dipole moment upon excitation (Δμ). By lengthening the polyenic chain, linear increases in excited-state dipoles are achieved while the ground-state dipole is maintained constant The polyenic chain thus allows for long-distance intramol. charge transfer. In addition, tuning of the magnitude of the ICT phenomenon and of the nonlinear responses is achieved by varying the donor and acceptor end groups: increasing the D/A strength leads to concomitant enhancements of Δμ, quadratic (β) and cubic (γ) hyperpolarizabilities values. Giant Δμ values (up to more than 30 D) and enhanced non-resonant quadratic and cubic NLO mol. responses (i.e. β(0)=500×10-30 esu and γ(0)=8000×10-36 esu) have been attained while maintaining suitable solubility, stability and transparency.

Chemical Physics published new progress about Bond order (alternation). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Application of C19H34O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Chand, Satish; Willis, Anthony C. published the artcile< (1S,2S)-1-(2-Bromo-4-hydroxy-3,5-dimethoxyphenyl)propane-1,2,3-triol>, Application In Synthesis of 112-63-0, the main research area is crystal structure bromohydroxydimethoxyphenylpropanetriol; mol structure bromohydroxydimethoxyphenylpropanetriol; hydrogen bond bromohydroxydimethoxyphenylpropanetriol.

(1S,2S)-1-(2-Bromo-4-hydroxy-3,5-dimethoxyphenyl)propane-1,2,3-triol, C11H15BrO6, is enantiomerically pure. The chirality at the stereogenic centers was installed via a Sharpless asym. dihydroxylation reaction and is S in each case. The crystal structure contains intermol. H-bonding interactions. Crystallog. data are given.

Acta Crystallographica, Section E: Structure Reports Online published new progress about Absolute configuration. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Application In Synthesis of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Fu, Yunxing; Zhang, Dezhong; Zhan, Hongmei; Zhao, Chenyang; Cheng, Yanxiang; Qin, Chuanjiang; Wang, Lixiang published the artcile< Engineering of Annealing and Surface Passivation toward Efficient and Stable Quasi-2D Perovskite Light-Emitting Diodes>, COA of Formula: C18H26O6, the main research area is perovskite light emitting diode annealing surface passivation.

Solution-processed quasi-two-dimensional (quasi-2D) perovskites with self-assembled multiple quantum well (QW) structures exhibit enhanced exciton binding energy, which is ideal for use as light emitters. Here, we have found that postannealing is important to promoting the QWs’ composition transfer, and we explored the correlation among the annealing time, the external quantum efficiency (EQE), and the operational stability of the device. During thermal annealing, the low-n QWs will gradually convert to high-n phases, accompanied by an increase in grain size. The EQE and working stability of the device exhibit different annealing-time dependences; i.e., with the extension of the annealing time, the EQE gradually decreases while the working stability improves. By introducing trimethylolpropane trimethacrylate (TPTA) to passivate the emitting-region defects, the annealing-time dependence of the EQE was effectively eliminated due to the reduction of the nonradiative recombination rate, wherefore high efficiency and stability can be achieved simultaneously. Our research provides an effective way to develop highly efficiency and stable perovskite light-emitting diodes.

Journal of Physical Chemistry Letters published new progress about Annealing. 3290-92-4 belongs to class esters-buliding-blocks, and the molecular formula is C18H26O6, COA of Formula: C18H26O6.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Jia, Xiao; Weber, Stefan; Schols, Dominique; Meier, Chris published the artcile< Membrane Permeable, Bioreversibly Modified Prodrugs of Nucleoside Diphosphate-γ-Phosphonates>, Application In Synthesis of 112-63-0, the main research area is DNA polymerase antiviral antitumor nucleotide preparation; antiviral anticancer phosphorylation metabolite phosphonate nucleoside HIV human; prodrug nucleoside phosphate phosphonate transcriptase inhibitor.

Nucleoside reverse transcriptase inhibitors (NRTIs) are widely used as antiviral and anticancer agents although they require intracellular phosphorylation into their antiviral active form, the triphosphorylated nucleoside analog metabolites. We report on the synthesis and characterization of a new class of nucleoside triphosphate analogs comprising a C-alkyl-phosphonate moiety replacing the γ-phosphate. These compounds were converted into bio-reversible modified lipophilic prodrugs at the γ-phosphonate by γ-C-(alkyl)-nucleoside triphosphate analogs with high selectivity due to an enzyme-triggered delivery mechanism. The later compounds were very stable in CEM cell extracts and they were substrates for HIV-RT without being substrates for DNA-polymerases α, β and γ. In antiviral assays, excellent antiviral activity of the prodrugs was found in CEM/0 cells was completely kept in CEM/TK- cells. The activity was improved by 3 logs as compared to the parent nucleoside d4T.

Journal of Medicinal Chemistry published new progress about AIDS (disease). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Application In Synthesis of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics