Preparation and characterization of novel functional tri-block copolymer for constructing temperature/redox dual-stimuli responsive micelles was written by Liu, Tianyue;Lang, Meidong. And the article was included in Journal of Macromolecular Science in 2022.Electric Literature of C13H10O3 The following contents are mentioned in the article:
Herein, we reported a novel tri-block copolymer synthesized by segmented ring-opening polymerization of temperature-sensitive 5-(pyrrolidine-1-carbonyl) oxepan-2-one monomer (VPyCL) and redox-sensitive macrocyclic disulfide-substituted carbonate monomer (MSS). The structure of the copolymers was confirmed by GPC, 1H NMR and 13C NMR. The obtained tri-block copolymers could self-assemble in aqueous solution to form well-structured micelles, with the mPEG-b-PVPyCL block acting as the hydrophilic coronal and the PSS block acting as the hydrophobic core. Dynamic light scattering (DLS) studies confirmed that micelles formed by these tri-block copolymers with different block ratios could respond to different temperature ranges during the heating/cooling process and respond to reducing agent glutathione (GSH). In addition, transmission electron microscopy (TEM) results further confirmed the polymeric micelles′ dual-stimuli responsiveness. The potential application of this type of dual-stimuli responsive micelles in drug delivery systems was evaluated using doxorubicin (DOX) as the model mol. The stimulus-dependent responsive behaviors of obtained micelles can be applied to the construction of smart materials capable of performing multiple functions under the appropriate conditions. This study involved multiple reactions and reactants, such as Diphenyl carbonate (cas: 102-09-0Electric Literature of C13H10O3).
Diphenyl carbonate (cas: 102-09-0) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Electric Literature of C13H10O3
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics