Alternating Chain Growth Copolymerization of Isothiocyanates and Epoxides was written by Song, Lidao;Liu, Mingqi;You, Donglei;Wei, Wei;Xiong, Huiming. And the article was included in Macromolecules (Washington, DC, United States) in 2021.Application In Synthesis of Isopropylisothiocyanate The following contents are mentioned in the article:
A class of heteroatom polymers through anionic chain growth copolymerization of epoxides and isothiocyanates has been successfully obtained under mild conditions via initiation by a simple salt of lithium alkoxide. The resulting polymers have characteristics of controlled mol. weights and low dispersity with a well-defined backbone of carbonimidothioate repeat units (-OC(=N)S-) at 100% alternating degree, which have been confirmed in the 1H-13C heteronuclear multiple bond correlation NMR spectrum and mass spectrum. Side reactions have been greatly suppressed in the copolymerization, and no more than 5% cyclic small mol. byproducts have been produced. We have revealed the special role of lithium bonds in regulating the alternating copolymerization of these two types of monomers, which are involved in activating isothiocyanates as well as binding the incoming monomers to the growing chain ends due to the especial coordination capability of lithium ions to multiple nucleophilic sites. The proposed mechanism of the alternating copolymerization process is supported by d. functional theory calculations Moreover, the copolymerization exhibits first-order kinetics with respect to the monomers and a quasi-living feature. Our strategy is expected to shed light on the incorporation of different types of cumulated double bonds as comonomers into polymer backbones, and the high availability of epoxides and isothiocyanates of various substitutions will forge the development of such kinds of heteropolymers. This study involved multiple reactions and reactants, such as Isopropylisothiocyanate (cas: 2253-73-8Application In Synthesis of Isopropylisothiocyanate).
Isopropylisothiocyanate (cas: 2253-73-8) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Application In Synthesis of Isopropylisothiocyanate
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics