El-Abadelah, Mustafa M. published the artcileHeterocycles [h]-fused onto 4-oxoquinoline-3-carboxylic acid. Part XII: synthesis of 5-fluoro-7-oxodihydro[1,3,4]thiadiazino[5,6-h]quinoline-8-carboxylic acid and ester, Formula: C7H13NO2, the publication is Zeitschrift fuer Naturforschung, B: A Journal of Chemical Sciences (2018), 73(1), 23-28, database is CAplus.
Direct interaction of dithizone with 7-chloro-6-fluoro-8-nitro-4-oxoquinoline-3-carboxylic acid and its ester delivered the corresponding novel 1,3,4-thiadiazino[5,6-h]quinoline-3-carboxylic acid and its ester I [R = H, Et] resp., alternatively latter ester derivative I [R = Et] was hydrolyzed to its acid derivative I [R = H]. Structures of the latter tricyclic hybrids I [R = H, Et] were deduced from anal. and spectral data and confirmed by single crystal X-ray structure determination of the compound I [R = Et]. The synthesized title compounds I [R = H, Et] were evaluated for antibacterial activity against Staphylococcus aureus ATCC 6538 and Escherichia coli ATCC 8739, antifungal activity against Candida albicans. Compound I [R = H] showed moderate activity against Staphylococcus aureus with a MIC value of 25 μg mL-1 and compounds I [R = H, Et] were inactive against Candida albicans.
Zeitschrift fuer Naturforschung, B: A Journal of Chemical Sciences published new progress about 924-99-2. 924-99-2 belongs to esters-buliding-blocks, auxiliary class Alkenyl,Amine,Aliphatic hydrocarbon chain,Ester, name is Ethyl 3-(dimethylamino)acrylate, and the molecular formula is C7H13NO2, Formula: C7H13NO2.
Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics