Application In Synthesis of 3-(Methoxycarbonyl)benzoic acidOn May 21, 2021 ,ãIridium-catalyzed C-H methylation and d3-methylation of benzoic acids with application to late-stage functionalizationsã?appeared in iScience. The author of the article were Weis, Erik; Hayes, Martin A.; Johansson, Magnus J.; Martin-Matute, Belen. The article conveys some information:
An iridium-catalyzed carboxylate-directed ortho C-H methylation and d3-methylation of benzoic acids was reported. The method used com. available reagents and precatalyst and requires no inert atm. or exclusion of moisture. Substrates bearing electron-rich and electron-poor groups were successfully methylated, including compounds with competing directing/coordinating groups. The method was also applied to the LSF of several marketed drugs, forming analogs with increased metabolic stability compared with the parent drug. In the part of experimental materials, we found many familiar compounds, such as 3-(Methoxycarbonyl)benzoic acid(cas: 1877-71-0Application In Synthesis of 3-(Methoxycarbonyl)benzoic acid)
3-(Methoxycarbonyl)benzoic acid(cas: 1877-71-0) belongs to esters. They are important in biology, being one of the main classes of lipids and comprising the bulk of animal fats and vegetable oils.Application In Synthesis of 3-(Methoxycarbonyl)benzoic acid They perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics