In 2019,Organic Letters included an article by Yasumoto, Kento; Kano, Taichi; Maruoka, Keiji. SDS of cas: 4248-19-5. The article was titled 《One-Pot Synthesis of Less Accessible N-Boc-Propargylic Amines through BF3-Catalyzed Alkynylation and Allylation Using Boronic Esters》. The information in the text is summarized as follows:
Alkynyl and alkenyl N-Boc propargylamines such as I (R = Ph, 4-MeOC6H4, 4-BrC6H4, 4-MeO2CC6H4, Bu, cyclohexyl, Me3Si) were prepared by alkynylation or allylation of N-Boc alkynyl aldimines (generated in situ from alkynals and BocNH2 or from N,N’-di-Boc aminals) with alkynyl or allyl diisopropylborates in the presence of BF3·Et2O at ambient temperature in CH2Cl2. The method allows N-Boc-propargylic amines to be obtained that are difficult to prepare by other methods. In the experimental materials used by the author, we found tert-Butyl carbamate(cas: 4248-19-5SDS of cas: 4248-19-5)
tert-Butyl carbamate(cas: 4248-19-5) belongs to anime. Nitrous acid converts secondary amines (aliphatic or aromatic) to N-nitroso compounds (nitrosamines): R2NH + HNO2 → R2N―NO. Some nitrosamines are potent cancer-inducing substances, and their possible formation is a serious consideration when nitrites, which are salts of nitrous acid, are present in foods or pharmaceutical preparations. Tertiary amines give rise to nitrosamines more slowly; an alkyl group is eliminated as an aldehyde or ketone, along with nitrous oxide, N2O.SDS of cas: 4248-19-5
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics