In 2019,Organic Letters included an article by Tsuji, Hiroaki; Hashimoto, Keisuke; Kawatsura, Motoi. Name: Diethyl 2-methylmalonate. The article was titled 《Nickel-Catalyzed Benzylic Substitution of Benzyl Esters with Malonates as a Soft Carbon Nucleophile》. The information in the text is summarized as follows:
The nickel-catalyzed benzylic substitution of benzyl alc. derivatives with a soft carbon nucleophile is extremely rare compared to that with a hard carbon nucleophile. The nickel-catalyzed benzylic substitution of benzyl esters with malonates as a soft carbon nucleophile is achieved. Primary and secondary benzyl 2,3,4,5,6-pentafluorobenzoates as well as a wide variety of malonate derivatives were well tolerated in the nickel-catalyzed reaction, providing the corresponding alkylation products in 46-86% yields (34 examples). Addnl., a possible reaction mechanism that would underwent via the η1- and η3-benzylnickel intermediates is proposed. After reading the article, we found that the author used Diethyl 2-methylmalonate(cas: 609-08-5Name: Diethyl 2-methylmalonate)
Diethyl 2-methylmalonate(cas: 609-08-5) belongs to aliphatic hydrocarbons. Aliphatic hydrocarbons belong to the most abundant fraction in crude oil. Aliphatics molecules are linear or branched open-chain structures such as n-alkanes, isoalkanes, cycloalkanes (naphthenes), terpenes and steranes.Name: Diethyl 2-methylmalonate
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics