The author of ãNi(0)-Catalyzed Three-Component Coupling Reaction of Tetrafluoroethylene and N-Sulfonyl-Substituted Imines with Silanes via Aza-Nickelacyclesã?were Shirataki, Hiroshi; Ono, Takafumi; Ohashi, Masato; Ogoshi, Sensuke. And the article was published in Organic Letters in 2019. Formula: C5H11NO2 The author mentioned the following in the article:
A nickel-catalyzed three-component coupling reaction of tetrafluoroethylene (TFE) and N-sulfonyl-substituted imines with silanes that furnishes a variety of fluorine-containing amines is disclosed. Stoichiometric experiments revealed that the aza-nickelacycles generated upon oxidative cyclization of TFE and N-sulfonyl-substituted imines on Ni(0) were identified as the key intermediates in this catalytic reaction. A single-crystal X-ray diffraction anal. of such an aza-nickelacycle revealed that the O atom of the N-sulfonyl group stabilizes the key intermediate via coordination to the nickel center. The experimental part of the paper was very detailed, including the reaction process of tert-Butyl carbamate(cas: 4248-19-5Formula: C5H11NO2)
tert-Butyl carbamate(cas: 4248-19-5) belongs to anime. To avoid the problem of multiple alkylation, methods have been devised for âblockingâ?substitution so that only one alkyl group is introduced. The Gabriel synthesis is one such method; it utilizes phthalimide, C6H4(CO)2NH, whose one acidic hydrogen atom has been removed upon the addition of a base such as KOH to form a salt.Formula: C5H11NO2
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics