On April 20, 2016, Wang, Cheng; Meng, Xiangshi; Gui, Bo published a patent.Reference of Dimethyl 2′-amino-[1,1′:4′,1”-terphenyl]-4,4”-dicarboxylate The title of the patent was Preparation method of light-controlled drug release metal organic framework compound. And the patent contained the following:
The invention provides a preparation method of light-controlled drug release metal organic framework compound, and the present invention makes azo ligand, acetic acid, and zirconium tetrachloride dissolved into N,N-DMF to obtain metal organic framework, and obtains the finished product by adding medicine and beta-cyclodextrin. Beta-cyclodextrin can combine with trans azo in the present invention, thus it makes the system have no release when it does not receive external stimulus, and makes release occur only after receiving UV radiation or adding amantadine, i.e. metal organic framework compound prepared by the present invention is capable of realizing controlled drug release. The experimental process involved the reaction of Dimethyl 2′-amino-[1,1′:4′,1”-terphenyl]-4,4”-dicarboxylate(cas: 1312703-30-2).Reference of Dimethyl 2′-amino-[1,1′:4′,1”-terphenyl]-4,4”-dicarboxylate
The Article related to light controlled drug release metal organic framework compound preparation, Inorganic Chemicals and Reactions: Coordination Compounds and other aspects.Reference of Dimethyl 2′-amino-[1,1′:4′,1”-terphenyl]-4,4”-dicarboxylate
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