On December 15, 2020, Yang, Xiaobao; Jiang, Biao; Song, Xiaoling; Sun, Ning; Ren, Chaowei; Kong, Ying; Zhang, Jianshui; Chen, Jinju; Li, Yan; Zhou, Yuedong published a patent.Reference of tert-Butyl 2-(2-(2-(tosyloxy)ethoxy)ethoxy)acetate The title of the patent was ALK protein regulator and anti-tumor application thereof. And the patent contained the following:
The invention relates a series of compounds designed and synthesized, have a wide range of pharmacol. activities,. The inventive compounds are capable of degrading specific proteins and/or inhibiting their activities, and can be applied to the treatment of tumor and cancer. The experimental process involved the reaction of tert-Butyl 2-(2-(2-(tosyloxy)ethoxy)ethoxy)acetate(cas: 882518-89-0).Reference of tert-Butyl 2-(2-(2-(tosyloxy)ethoxy)ethoxy)acetate
The Article related to alk protein brigatinib alecensa phosphine oxide derivative preparation, antitumor activity brigatinib alecensa phosphine oxide derivative, Organometallic and Organometalloidal Compounds: Phosphorus Compounds and other aspects.Reference of tert-Butyl 2-(2-(2-(tosyloxy)ethoxy)ethoxy)acetate
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics