Niguez, Diego Ros; Khazaeli, Pegah; Alonso, Diego A.; Guillena, Gabriela published an article in 2018, the title of the article was Deep eutectic mixtures as reaction media for the enantioselective organocatalyzed α-amination of 1,3-dicarbonyl compounds.Application In Synthesis of 3-Acetyldihydrofuran-2(3H)-one And the article contains the following content:
The enantioselective α-amination of 1,3-dicarbonyl compounds was performed using deep eutectic solvents (DES) as a reaction media and chiral 2-amino benzimidazole-derived compounds as a catalytic system to afford amino 1,3-dicarbonyl compounds, e.g., I. With this procedure, the use of toxic volatile organic compounds (VOCs) as reaction media was avoided. Furthermore, highly functionalized chiral mols., which were important intermediates for the natural product synthesis, were synthesized by an efficient and stereoselective protocol. Moreover, the reaction could be done on a preparative scale, with the recycling of the catalytic system being possible for at least five consecutive reaction runs. This procedure represented a cheap, simple, clean, and scalable method that meets most of the principles to be considered a green and sustainable process. The experimental process involved the reaction of 3-Acetyldihydrofuran-2(3H)-one(cas: 517-23-7).Application In Synthesis of 3-Acetyldihydrofuran-2(3H)-one
The Article related to amino dicarbonyl compound green preparation enantioselective, dicarbonyl compound azodicarboxylate chiral amino benzimidazole catalyst amination sonication, Alicyclic Compounds: Cyclopentanes, Including Fulvenes and Fulvalenes and other aspects.Application In Synthesis of 3-Acetyldihydrofuran-2(3H)-one
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics