Yuan, Zaifeng; Li, Na; Zhu, Chunyu; Xia, Chengfeng published an article in 2018, the title of the article was Copper-catalyzed synthesis of α-amino nitriles through methyl transfer from DMF to aromatic amines.Application of 85-91-6 And the article contains the following content:
Synthesis of α-amino nitriles RR1NCH2CN [R = C6H5, 4-ClC6H4, 1-naphthyl, etc.; R1 = CH3, C2H5, c-C6H11, etc.] and α-amino nitriles, e.g., I via copper-catalyzed activation of C(sp3)-H bonds of DMF at room temperature, which resulted in Me transfer to aromatic amines followed by cyanation was described. This process featured excellent functional group tolerance, broad substrate scope and high activity under ambient conditions. The experimental process involved the reaction of Methyl N-Methylanthranilate(cas: 85-91-6).Application of 85-91-6
The Article related to alpha amino nitrile preparation, secondary aromatic amine dimethyl formamide cyanation copper catalyst, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Nitriles, Isonitriles, and Acyl Cyanides and other aspects.Application of 85-91-6
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