On January 31, 2022, Miltojevic, Ana B.; Mitic, Katarina V.; Stojanovic, Nikola M.; Randjelovic, Pavle J.; Radulovic, Niko S. published an article.Recommanded Product: Methyl N-Methylanthranilate The title of the article was Methyl and Isopropyl N-Methylanthranilates Affect Primary Macrophage Function – An Insight into the Possible Immunomodulatory Mode of Action. And the article contained the following:
To complement the knowledge on the anti-inflammatory activity of Me and iso-Pr N-methylanthranilates, two natural products with panacea-like properties, we investigated their effects on thioglycolate-elicited macrophages by evaluating macrophage ability to metabolize MTT, macrophage membrane function, and macrophage myeloperoxidase and phagocytic activities. Moreover, two addnl. aspects of the inflammatory response of these compounds, their inhibitory activity on xanthine oxidase and catalase, were studied. It was found that these two compounds regulate elicited macrophage functions, most probably by interfering with the function of cell membranes and changing the reducing cellular capacity or enzyme activity of macrophages. Nonetheless, no significant inhibitory action either towards xanthine oxidase or catalase was found, suggesting that the inhibition of these enzymes is not involved in the anti-inflammatory mode of action of these two esters. The experimental process involved the reaction of Methyl N-Methylanthranilate(cas: 85-91-6).Recommanded Product: Methyl N-Methylanthranilate
The Article related to methyl isopropyl n methylanthranilate macrophage, n-methylanthranilic acid esters, anti-inflammatory activity, immunomodulatory potential, macrophage function, oxidoreductases and other aspects.Recommanded Product: Methyl N-Methylanthranilate
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