On March 22, 2022, Ma, Yuanhong; Tang, Ling published a patent.Electric Literature of 93476-46-1 The title of the patent was Preparation of arylcyclo[a]carbazoles and arylcyclo[g]pyridine indoles. And the patent contained the following:
The invention discloses the preparation method of arylcyclo[a]carbazole compounds with general formula I and arylcyclo[g]pyridine indole compounds with general formula II [where R1 = hydrogen, alkyl, substituted aryl, substituted heteroaryl, acyl, alkyl amide, alkyl ether, alkylthio, ester, alkylamino, alkenyl or alkynyl; R2 = alkyl, substituted aryl, substituted heteroaryl or alkyl ether; R3 = hydrogen, alkyl, substituted aryl, substituted heteroaryl, acyl, alkylamide, alkyl ether, alkylthio, ester, alkylamino, alkenyl or alkynyl; R4 = hydrogen, alkyl, substituted aryl or alkynyl heteroaryl or acyl; Ar = substituted aryl or substituted heteroaryl; R5 = alkyl acyl, arylacyl, ester or cyano; R6 = hydrogen, alkyl, substituted aryl, substituted heteroaryl, acyl, alkyl amide, alkyl ether, alkylthio, ester, alkylamino, alkenyl or alkynyl], which has the following advantages: mild reaction conditions, simple operation, wide source of raw materials, high utilization value of products, and is conducive to industrial production For example, 11-methyl-6-phenyl-11H-benzo[a]carbazole was prepared by oxidative cyclization of 1-methyl-1H-indole and 2-(2-oxo-2-phenylethyl)benzonitrile. The experimental process involved the reaction of Ethyl indolizine-1-carboxylate(cas: 93476-46-1).Electric Literature of 93476-46-1
The Article related to bronsted acid preparation benzonitrile indolizine indole carbazole oxidative cyclization, Heterocyclic Compounds (One Hetero Atom): Indoles, Indolizines, Carbazoles, and Other Arenopyrroles and other aspects.Electric Literature of 93476-46-1
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