Hu, Huayou; Liu, Yun; Zhong, Hao; Zhu, Yulan; Wang, Chao; Ji, Min published an article in 2012, the title of the article was Heck-Type Cross-Dehydrogenative Coupling Reactions of Indolizines at the 3-Position with Electron-Deficient Alkenes through Palladium-Catalyzed C-H Activation.Formula: C11H11NO2 And the article contains the following content:
Palladium-catalyzed Heck-type cross-dehydrogenative coupling reactions of indolizines with electron-deficient alkenes gave 3-alkenyl substituted indolizines. E.g., in presence of Pd(OAc)2 as catalyst, Cu(OAc)2 as oxidant, and KHCO3 as base, reaction of indolizine (I) with Et acrylate gave up to 82.3% 3-alkenyl substituted indolizine (II) as the (E)-isomer. The reaction took place at the 3-position through Pd-catalyzed C-H activation. The experimental process involved the reaction of Ethyl indolizine-1-carboxylate(cas: 93476-46-1).Formula: C11H11NO2
The Article related to palladium catalyst dehydrogenative coupling reaction indolizine electron deficient alkene, Heterocyclic Compounds (One Hetero Atom): Indoles, Indolizines, Carbazoles, and Other Arenopyrroles and other aspects.Formula: C11H11NO2
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