On November 30, 1981, Fujisawa, Seiichiro; Masuhara, Eiichi published an article.Quality Control of 2,2-Dimethylpropane-1,3-diyl bis(2-methylacrylate) The title of the article was Determination of partition coefficients of acrylates, methacrylates, and vinyl monomers using high performance liquid chromatography (HPLC). And the article contained the following:
Retention times (Rt) for acrylates, methacrylates, and vinyl monomers were measured with 2 different columns (C18 Corasil and C8 LiChrosorb) using reverse-phase HPLC in order to obtain their partition coefficients between 1-octanol and water (log P). The log P values of test compounds were determined from the regression curves between Rt and log P values of a number of standards using C8 LiChrosorb. The log P values obtained in this manner agreed closely with the log P values observed in previous studies. However, the peaks of these compounds were not sharp and some compounds were eluted for > 10 min. Thus, the measurement of accurate Rt values is tedious. C18 Corasil was therefore used in a mobile phase (MeOH-H2O 85:15). The Rt of some methacrylates with P values over 4 were delayed due to the hydrophobic interaction between these compounds and the C18 packing material. However, in the measurable region of the log P values (about -1 to +4), log P correlated linearly with log Rt following 2 different regression curves: one for aliphatic and aromatic compounds with the functional groups (r = 0.92), and the other for compounds without these groups (r = 0.99). Log P values of methacrylates widely used in dentistry can be determined easily and accurately by HPLC. The experimental process involved the reaction of 2,2-Dimethylpropane-1,3-diyl bis(2-methylacrylate)(cas: 1985-51-9).Quality Control of 2,2-Dimethylpropane-1,3-diyl bis(2-methylacrylate)
The Article related to partition coefficient acrylate monomer, liquid chromatog acrylate monomer, methacrylate monomer liquid chromatog, vinyl monomer liquid chromatog, dental monomer partition coefficient and other aspects.Quality Control of 2,2-Dimethylpropane-1,3-diyl bis(2-methylacrylate)
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