Murphy, Nicie Conley; Compton, Robert N.; Pagni, Richard M. published the artcile< Effect of Chiral and Achiral Perturbations on the Crystallization of 4,4'-Dimethylchalcone from Ethyl Acetate>, HPLC of Formula: 112-63-0, the main research area is beta radiolysis polarized light effect crystallization methylchalcone; optical activity achiral mol manipulation synthetic photochem method; chiral achiral perturbation effect crystallization methylchalcone Et acetate.
4,4′-Dimethylchalcone is an achiral mol. that crystallizes from Et acetate in the chiral space group P212121. The authors report the effect of β-radiolysis and circularly and linearly polarized light on the crystallization of 4,4′-dimethylchalcone from Et acetate. Exposure of the evaporating solution to energetic β-particles from a Sr-90 source generated a random distribution of (+) and (-) crystals. Irradiation of the evaporating solution by intense right- or left-circularly polarized light (1064 nm) from a Nd:YAG laser afforded results that were comparable to the results of the β-radiolysis experiments Linearly polarized light (LPL), on the other hand, had a profound influence on the distribution of crystals, yielding in this instance a large bifurcation of (+) and (-) crystals. A likely cause of this outcome may be due to the optical Kerr effect. The anisotropic polarizability of the chalcone mol. causes a preferential alignment in the direction of the E field when using LPL. This mol. alignment results in a sizable enantiomeric excess. Circularly polarized light does not produce the alignment of the chalcone and thus has no effect on the asym. induction. This alignment offers an opportunity for chirally autocatalytic secondary nucleation to occur, which is then able to amplify small initial asymmetry in the number of (+) and (-) crystals. The chirality of the chalcone crystals was determined via their reaction in water with pyridinium tribromide to yield the chiral compound erythro-1,2-dibromo-4,4′-dimethylchalcone, thus allowing the chirality of the crystal to be propagated to mol. chirality.
Crystal Growth & Design published new progress about Chirality. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, HPLC of Formula: 112-63-0.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics