Tong, Guanghu; Zhu, Bo; Lee, Richmond; Yang, Wenguo; Tan, Davin; Yang, Caiyun; Han, Zhiqiang; Yan, Lin; Huang, Kuo-Wei; Jiang, Zhiyong published the artcile< Highly Enantio- and Diastereoselective Allylic Alkylation of Morita-Baylis-Hillman Carbonates with Allyl Ketones>, Reference of 112-63-0, the main research area is enantioselective diastereoselective allylic alkylation MBH carbonate allyl ketone; Morita Baylis Hillman carbonate enantioselective diastereoselective allylic alkylation; regioselective allylic alkylation MBH carbonate allyl ketone.
The asym. allylic alkylation of Morita-Baylis-Hillman (MBH) carbonates with allyl ketones has been developed. The α-regioselective alkylation adducts, containing a hexa-1,5-diene framework with important synthetic value, were achieved in up to 83% yield, >99% ee, and 50:1 dr by using a com. available Cinchona alkaloid as the catalyst (e.g., I + II → III). From the allylic alkylation adduct, a cyclohexene bearing two adjacent chiral centers was readily prepared (III → IV).
Journal of Organic Chemistry published new progress about Alkadienes Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Reference of 112-63-0.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics