Tandon, Vishnu K.; Van Leusen, Albert M.; Wynberg, Hans published the artcile< Synthesis of enantiomerically pure (S)-(+)-3-hydroxytetrahydrofuran, and its (R)-enantiomer, from malic or tartaric acid>, Safety of (S)-Dimethyl 2-hydroxysuccinate, the main research area is furanol tetrahydro enantiomer; hydroxytetrahydrofuran enantiomer; butanetriol cyclodehydration.
The title compounds [(S)- and (R)-I] were prepared in high yield and high enantiomeric purity by cyclodehydration of (S)- and (R)-1,2,4-butanetriol, resp. Thus, (S)-HO2CCH(OH)CH2CO2H was esterified and reduced with LiAlH4 to give the (S)-triol, which was treated with 4-MeC6H4SO3H to give 87% (S)-I.
Journal of Organic Chemistry published new progress about Cyclization. 617-55-0 belongs to class esters-buliding-blocks, and the molecular formula is C6H10O5, Safety of (S)-Dimethyl 2-hydroxysuccinate.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics