Borthwick, Alan D’s team published research in Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999) in 1973 | 112-63-0

Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999) published new progress about Deamination. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Product Details of C19H34O2.

Borthwick, Alan D.; Foxton, Michael W.; Gray, Brian V.; Gregory, Gordon I.; Seale, Peter W.; Warburton, William K. published the artcile< 2-Nitrothizaoles>, Product Details of C19H34O2, the main research area is nitrothiazole bactericide; thiazole nitro bactericide; oxadiazole nitrothiazolyl bactericide; deamination aminothiazolyloxadiazole nitro Sandmeyer.

2-Nitrothiazole-5-carboxaldehyde oxime (I; R = CH:NOH) with propene oxide and COCl2 gave 60.5% I (R = CN) which with NH2OH gave 69% I [R = C(:NOH)NH2]. The latter with CH(OEt)3 and BF3.Et2O gave 48.5% 3-(2-nitrothiazol-5-yl)-1,2,4-oxadiazole (II; R = NO2, R1 = H). II (R = NH2, R1 = H), prepared in 4 steps from 2-aminothiazole-5-carboxaldehyde, with Cu and HNO2 gave 41% II (R = NO2, R1 = H) and 6% II (R = R1 = H). Similarly II (R = NH2, R1 = Me) gave 25% II (R = NO2, R1 = Me) and 20% II (R = H, R1 = Me). I (R = CHO) with 1,2,4-oxadiazol-3-ylmethyltriphenylphosphonium chloride and its 5-Me derivative gave 58 and 34% oxadizoles (III, R = H, and Me, resp.). The latter 2 compounds and II (R = NO2, R1 = H and Me) showed powerful antibacterial properties.

Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999) published new progress about Deamination. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Product Details of C19H34O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics