Hayashi, H.; Nakanishi, K.; Brandon, C.; Marmur, J. published the artcile< Structure and synthesis of dihydroxypentyluracil from bacteriophage SP-15 deoxyribonucleic acid>, Name: (S)-Dimethyl 2-hydroxysuccinate, the main research area is bacteriophage dihydroxypentyluracil; ribonucleic acid bacteriophage SP15.
(S)-(+)-5-(4′,5′-Dihydroxypentyl)uracil, a base which replaces thymine in bacteriophage SP-15 DNA was prepared starting from (S)-(-)-malic acid establishing the 4′ configuration as being (S). The optical purity (100%) of a synthetic intermediate PhCH:CH(CH2)2CH(OMTPA)CH2OMTPA [MTPA = (+)-MeOCH(CF3)CO] was checked by NMR.
Journal of the American Chemical Society published new progress about DNA Role: RCT (Reactant), RACT (Reactant or Reagent). 617-55-0 belongs to class esters-buliding-blocks, and the molecular formula is C6H10O5, Name: (S)-Dimethyl 2-hydroxysuccinate.
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