Dias, Luiz C.; Vieira, Adriano S.; Barreiro, Eliezer J. published the artcile< The total synthesis of calcium atorvastatin>, Recommanded Product: (S)-Dimethyl 2-hydroxysuccinate, the main research area is calcium atorvastatin preparation.
A practical and convergent asym. route to calcium atorvastatin was reported. The synthesis of calcium atorvastatin was performed using the remote 1,5-anti asym. induction in the boron-mediated aldol reaction of β-alkoxy methylketone with pyrrolic aldehyde as a key step. Calcium atorvastatin was obtained from aldehyde after 6 steps, with a 41% overall yield.
Organic & Biomolecular Chemistry published new progress about Aldol condensation, stereoselective. 617-55-0 belongs to class esters-buliding-blocks, and the molecular formula is C6H10O5, Recommanded Product: (S)-Dimethyl 2-hydroxysuccinate.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics